{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:02:44Z","timestamp":1740164564310,"version":"3.37.3"},"reference-count":5,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>The objectives of this paper are to discuss a rare cause of laryngeal multiple myeloma, to review unique pathologic findings associated with plasma cell neoplasms, to discuss epidemiology, differential diagnosis, and treatment options for plasma cell neoplasms of the larynx. Laryngeal multiple myeloma, also noted in the literature as \u201cmetastatic\u201d multiple myeloma, presenting as a de novo laryngeal mass is extremely rare with few reported cases. Laryngeal involvement of extramedullary tumors is reported to be between 6% and 18% with the epiglottis, glottis, false vocal folds, aryepiglottic folds, and subglottis involved in decreasing the order of frequency. We present the case of a 58-year-old male with a history of IgA smoldering myeloma who presented to a tertiary care laryngological practice with a two-month history of dysphonia, which was found to be laryngeal involvement of multiple myeloma. We review the classification of and differentiation between different plasma cell neoplasms, disease workups, pathologic findings, and treatment options.<\/jats:p>","DOI":"10.1155\/2012\/257814","type":"journal-article","created":{"date-parts":[[2012,11,18]],"date-time":"2012-11-18T16:00:17Z","timestamp":1353254417000},"page":"1-3","source":"Crossref","is-referenced-by-count":2,"title":["Laryngeal Involvement of Multiple Myeloma"],"prefix":"10.1155","volume":"2012","author":[{"given":"Ariel B.","family":"Grobman","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Suite 572, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Vivero","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Suite 572, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"German","family":"Campuzano-Zuluaga","sequence":"additional","affiliation":[{"name":"Department of Pathology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, 14th Floor, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parvin","family":"Ganjei-Azar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, 14th Floor, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4289-0158","authenticated-orcid":true,"given":"David E.","family":"Rosow","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Suite 572, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"volume-title":"Plasma cell neoplasms","year":"2008","key":"1"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199706000-00007"},{"issue":"5","key":"3","first-page":"309","volume":"14","year":"1985","journal-title":"Journal of Otolaryngology"},{"issue":"3","key":"4","first-page":"570","volume":"17","year":"1996","journal-title":"American Journal of Neuroradiology"},{"issue":"5","key":"5","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1046\/j.1365-2141.2003.04355.x","volume":"121","year":"2003","journal-title":"British Journal of Haematology"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2012\/257814.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2012\/257814.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2012\/257814.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T22:50:05Z","timestamp":1497999005000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crionm\/2012\/257814\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":5,"alternative-id":["257814","257814"],"URL":"https:\/\/doi.org\/10.1155\/2012\/257814","relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"type":"print","value":"2090-6706"},{"type":"electronic","value":"2090-6714"}],"subject":[],"published":{"date-parts":[[2012]]}}}