{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:54:38Z","timestamp":1782280478983,"version":"3.54.5"},"reference-count":14,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To report the 12-month follow-up after big-bubble deep anterior lamellar keratoplasty (DALK) assisted by femtosecond laser that we have called IntraBubble.<jats:italic>Methods<\/jats:italic>. A 60\u2009kHz IntraLase femtosecond laser (Abbott Medical Optics) firstly created a 30<jats:sup>\u00b0<\/jats:sup>angled intrastromal channel to insert the air injection cannula, 50\u2009\u03bc above the thinnest corneal site measured by Sirius Scheimpflug camera (CSO, Firenze, Italy), then performed a full lamellar cut 100\u2009\u03bc above the thinnest corneal point, and from the same corneal depth, created a mushroom incision. The lamella was removed, and the smooth cannula of Fogla was inserted into the stromal channel and air was injected to achieve a big bubble. The follow up is 12 months, and sutures were removed by the 10th postoperative month in all patients. Best Corrected Visual Acuity (BCVA), spherical equivalent and, by Sirius Scheimpflug camera (CSO, Firenze, Italy) keratometric astigmatism were evaluated.<jats:italic>Results<\/jats:italic>. All procedures were completed as DALK except 2 converted to PK because an inadvertent intraoperative macroperforation occurred. Mean postoperative BCVA was 0.8, mean spherical equivalent was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn>-<\/mml:mn><mml:mn>3.5<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>1.7<\/mml:mn><mml:mi>\u2009<\/mml:mi><\/mml:math>D, and mean keratometric astigmatism was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn>4.8<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>3.1<\/mml:mn><mml:mi>\u2009<\/mml:mi><\/mml:math>D.<jats:italic>Conclusion<\/jats:italic>. The femtosecond laser could standardize the big-bubble technique in DALK, reducing the risk of intraoperative complications and allowing good refractive outcomes.<\/jats:p>","DOI":"10.1155\/2012\/264590","type":"journal-article","created":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T21:03:25Z","timestamp":1328821405000},"page":"1-4","source":"Crossref","is-referenced-by-count":23,"title":["Femtosecond Laser and Big-Bubble Deep Anterior Lamellar Keratoplasty: A New Chance"],"prefix":"10.1155","volume":"2012","author":[{"given":"Luca","family":"Buzzonetti","sequence":"first","affiliation":[{"name":"Ophthalmology Department, Bambino Ges\u00f9 Children\u2019s Hospital, Via Torre di Palidoro snc, Passoscuro, 00050 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianni","family":"Petrocelli","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Bambino Ges\u00f9 Children\u2019s Hospital, Via Torre di Palidoro snc, Passoscuro, 00050 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Valente","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Bambino Ges\u00f9 Children\u2019s Hospital, Via Torre di Palidoro snc, Passoscuro, 00050 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"issue":"7","key":"1","doi-asserted-by":"crossref","first-page":"653","DOI":"10.3928\/1081-597X-19971101-12","volume":"13","year":"1997","journal-title":"Journal of Refractive Surgery"},{"issue":"4","key":"2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3928\/1081-597X-20070401-04","volume":"23","year":"2007","journal-title":"Journal of Refractive Surgery"},{"issue":"1","key":"3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3928\/1081597X-20080101-03","volume":"24","year":"2008","journal-title":"Journal of Refractive Surgery"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31815a50bf"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00067-1"},{"issue":"3","key":"6","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bjo.81.3.184","volume":"81","year":"1997","journal-title":"British Journal of Ophthalmology"},{"issue":"3","key":"7","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/bjo.83.3.327","volume":"83","year":"1999","journal-title":"British Journal of Ophthalmology"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200205000-00009"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-199908000-00006"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01181-6"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.08.013"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.02.036"},{"key":"13"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181a186c0"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2012\/264590.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2012\/264590.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2012\/264590.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T13:08:29Z","timestamp":1640696909000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/joph\/2012\/264590\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":14,"alternative-id":["264590","264590"],"URL":"https:\/\/doi.org\/10.1155\/2012\/264590","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}