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In all patients monocular stimulation of affected and unaffected eye elicited significantly different activation foci in the primary visual cortex (V1), whereas the foci evoked in the middle temporal visual area (area V5) were similar in size and in delay of blood-oxygen-level-dependent response. DTI analysis documented lower white matter anisotropy values and reduced fibre reconstruction in the affected compared with the unaffected optic nerves. The preserved activation of area V5 observed in all our patients is an interesting finding that suggests the notion of a different sensitivity of the optic pathways to inflammatory changes.<\/jats:p>","DOI":"10.1155\/2012\/265306","type":"journal-article","created":{"date-parts":[[2012,7,18]],"date-time":"2012-07-18T20:16:29Z","timestamp":1342642589000},"page":"1-7","source":"Crossref","is-referenced-by-count":8,"title":["Functional MRI Examination of Visual Pathways in Patients with Unilateral Optic Neuritis"],"prefix":"10.1155","volume":"2012","author":[{"given":"Giulia","family":"Mascioli","sequence":"first","affiliation":[{"name":"Sezione Scienze Radiologiche, Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Universit\u00e0 Politecnica delle Marche, Via Tronto 10\/A, 60126 Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Salvolini","sequence":"additional","affiliation":[{"name":"Sezione Neuroscienze Cliniche, 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