{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:25:28Z","timestamp":1740147928763,"version":"3.37.3"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61025019","90820016","NECT-07-0735"],"award-info":[{"award-number":["61025019","90820016","NECT-07-0735"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61025019","90820016","NECT-07-0735"],"award-info":[{"award-number":["61025019","90820016","NECT-07-0735"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"New Century Excellent Talents in University","award":["61025019","90820016","NECT-07-0735"],"award-info":[{"award-number":["61025019","90820016","NECT-07-0735"]}]},{"name":"Natural Science Foundation of Hebei, China","award":["61025019","90820016","NECT-07-0735"],"award-info":[{"award-number":["61025019","90820016","NECT-07-0735"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>This paper presents an alternative method, called as parallel factor analysis (PARAFAC) with a continuous wavelet transform, to analyze of brain activity in patients with chronic pain in the time-frequency-channel domain and quantifies differences between chronic pain patients and controls in these domains. The event related multiple EEG recordings of the chronic pain patients and non-pain controls with somatosensory stimuli (pain, random pain, touch, random touch) are analyzed. Multiple linear regression (MLR) is applied to describe the effects of aging on the frequency response differences between patients and controls. The results show that the somatosensory cortical responses occurred around 250\u2009ms in both groups. In the frequency domain, the neural response frequency in the pain group (around 4\u2009Hz) was less than that in the control group (around 5.5\u2009Hz) under the somatosensory stimuli. In the channel domain, cortical activation was predominant in the frontal region for the chronic pain group and in the central region for controls. The indices of active ratios were statistical significant between the two groups in the frontal and central regions. These findings demonstrate that the PARAFAC is an interesting method to understanding the pathophysiological characteristics of chronic pain.<\/jats:p>","DOI":"10.1155\/2012\/279560","type":"journal-article","created":{"date-parts":[[2012,2,2]],"date-time":"2012-02-02T16:00:43Z","timestamp":1328198443000},"page":"1-10","source":"Crossref","is-referenced-by-count":8,"title":["Characteristics of Evoked Potential Multiple EEG Recordings in Patients with Chronic Pain by Means of Parallel Factor Analysis"],"prefix":"10.1155","volume":"2012","author":[{"given":"Juan","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China"},{"name":"National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 10088, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengbiao","family":"Lu","sequence":"additional","affiliation":[{"name":"Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Logan J.","family":"Voss","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Waikato Hospital, Hamilton 3204, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P. 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