{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:50:00Z","timestamp":1791445800358,"version":"4.3.3"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>\n                    <jats:italic>Purpose.<\/jats:italic>\n                    Application of anterior segment optical coherence (AS-OCT) in pediatric ophthalmology.\n                    <jats:italic>Methods.<\/jats:italic>\n                    Retrospective clinical study case series of 26 eyes of 19 pediatric patients throughout a 21-month period, presenting anterior segment pathologies, were submitted to AS-OCT examination (OCT Visante, 1310\u2009nm, Zeiss), noncontact technique, no sedation requirement.\n                    <jats:italic>Results.<\/jats:italic>\n                    AS-OCT images were obtained from 19 patients (range: 2 months to 12 years). Clinical diagnosis of anterior segment abnormalities included cornea disease (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>7<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), congenital anterior segment conditions (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>10<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), ocular trauma (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>1<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), anterior segment surgeries (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>2<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), iridocorneal angle abnormalities (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>4<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), intermediate uveitis (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>2<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). The most common OCT findings were corneal hyperreflectivity and thickening (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>15<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), shallow anterior chamber with iris-lens diaphragm anterior displacement (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>4<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), atypical corneal curvature (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>4<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), corneal thinning (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>4<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), peripheral synechiae with angle closure (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>3<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), increased anterior chamber depth (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>2<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ), and proximal portion of glaucoma drainage tube (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\">\n                      <mml:mrow>\n                        <mml:mi>n<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>2<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ).\n                    <jats:italic>Conclusion.<\/jats:italic>\n                    In the present study, noncontact AS-OCT demonstrated to be a feasible technique to evaluate the anterior segment providing anatomic details and useful to clarify diagnosis in the pediatric population.\n                  <\/jats:p>","DOI":"10.1155\/2012\/313120","type":"journal-article","created":{"date-parts":[[2012,8,9]],"date-time":"2012-08-09T17:01:36Z","timestamp":1344531696000},"page":"1-6","source":"Crossref","is-referenced-by-count":36,"title":["Application of Anterior Segment Optical Coherence Tomography in Pediatric Ophthalmology"],"prefix":"10.1155","volume":"2012","author":[{"given":"Ricardo Salles","family":"Cauduro","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo (UNIFESP), 04023-062 S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline do Amaral","family":"Ferraz","sequence":"additional","affiliation":[{"name":"Fleury Medicina e Sa\u00fade, Ophthalmology Diagnostic Center, 04501-900 S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maira Saad \u00c1vila","family":"Morales","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo (UNIFESP), 04023-062 S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia Novita","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo (UNIFESP), 04023-062 S\u00e3o Paulo, Brazil"},{"name":"Department of Ophthalmology, Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo, 01221-020 S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yara Cristina","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo (UNIFESP), 04023-062 S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Henrique","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo (UNIFESP), 04023-062 S\u00e3o Paulo, Brazil"},{"name":"Fleury Medicina e Sa\u00fade, Ophthalmology Diagnostic Center, 04501-900 S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma","family":"Allemann","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Federal University of S\u00e3o Paulo (UNIFESP), 04023-062 S\u00e3o Paulo, Brazil"},{"name":"Fleury Medicina e Sa\u00fade, Ophthalmology Diagnostic Center, 04501-900 S\u00e3o Paulo, Brazil"},{"name":"Department of Ophthalmology & Visual Sciences, University of Illinois at Chicago, Chicago 60612, 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