{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:48:35Z","timestamp":1790707715697,"version":"4.1.0"},"reference-count":44,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical and Developmental Immunology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>The authors present their experience related to the diagnosis, treatment, and followup of 431 patients with bullous pemphigoid, 14 patients with juvenile bullous pemphigoid, and 273 patients with pemphigus. The detection of autoantibodies plays an outstanding role in the diagnosis and differential diagnosis. Paraneoplastic pemphigoid is suggested to be a distinct entity from the group of bullous pemphigoid in view of the linear C3 deposits along the basement membrane of the perilesional skin and the \u201cladder\u201d configuration of autoantibodies demonstrated by western blot analysis. It is proposed that IgA pemphigoid should be differentiated from the linear IgA dermatoses. Immunosuppressive therapy is recommended in which the maintenance dose of corticosteroid is administered every second day, thereby reducing the side effects of the corticosteroids. Following the detection of IgA antibodies (IgA pemphigoid, linear IgA bullous dermatosis, and IgA pemphigus), diamino diphenyl sulfone (dapsone) therapy is preferred alone or in combination. The clinical relevance of autoantibodies in patients with autoimmune bullous dermatosis is stressed.<\/jats:p>","DOI":"10.1155\/2012\/369546","type":"journal-article","created":{"date-parts":[[2012,12,24]],"date-time":"2012-12-24T21:00:47Z","timestamp":1356382847000},"page":"1-9","source":"Crossref","is-referenced-by-count":19,"title":["Clinical Relevance of Autoantibodies in Patients with Autoimmune Bullous Dermatosis"],"prefix":"10.1155","volume":"2012","author":[{"given":"Lilla","family":"Mih\u00e1lyi","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology, Albert Szent-Gy\u00f6rgyi Medical Center, University of Szeged, Kor\u00e1nyi Fasor 6, 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1ria","family":"Kiss","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology, Albert Szent-Gy\u00f6rgyi Medical Center, University of Szeged, Kor\u00e1nyi Fasor 6, 6720 Szeged, 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