{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T18:55:49Z","timestamp":1740164149239,"version":"3.37.3"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>The numbers of syphilis cases have been increasing considerably, especially in eastern europe, thereby contributing towards greater chances of cases of congenital syphilis. Some of the complications of congenital syphilis can be detected on two-dimensional ultrasonography (2DUS), and these are generally manifested in the second trimester of pregnancy. The commonest ultrasonographic signs are hepatosplenomegaly, placentomegaly, and fetal growth restriction, while lower-frequency occurrences include intrahepatic calcifications, ascites, fetal hydrops, and even fetal death. Three-dimensional ultrasonography (3DUS) is a relatively new imaging technique that is adjuvant to 2DUS and enables detailed assessment of the fetal surface anatomy. We present a case of a 21-year-old primigravida with a diagnosis of congenital syphilis, with obstetric 2DUS findings of hepatosplenomegaly, ascites, pericardial effusion and hyperechogenicity of the cerebral parenchyma. 3DUS in rendering mode allowed clear assessment of the fetal limbs, especially the feet, which appeared twisted and lacked some toes. It allowed the parents to understand the pathological condition better and improved prenatal management and neonatal followup. 3DUS can be used routinely for assessing fetal malformations resulting from congenital infections.<\/jats:p>","DOI":"10.1155\/2012\/478436","type":"journal-article","created":{"date-parts":[[2012,8,21]],"date-time":"2012-08-21T18:13:27Z","timestamp":1345572807000},"page":"1-3","source":"Crossref","is-referenced-by-count":1,"title":["Prenatal Diagnosis of Congenital Syphilis Using Two- and Three-Dimensional Ultrasonography: Case Report"],"prefix":"10.1155","volume":"2012","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6145-2532","authenticated-orcid":true,"given":"Edward","family":"Araujo J\u00fanior","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Federal University of S\u00e3o Paulo (UNIFESP), Rua Carlos Weber, 956 apto. 113 Visage, Vila Leopoldina, S\u00e3o Paulo 05303-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Felix","family":"Martins Santana","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Federal University of S\u00e3o Paulo (UNIFESP), Rua Carlos Weber, 956 apto. 113 Visage, Vila Leopoldina, S\u00e3o Paulo 05303-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8739-4115","authenticated-orcid":true,"given":"Liliam Cristine","family":"Rolo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Federal University of S\u00e3o Paulo (UNIFESP), Rua Carlos Weber, 956 apto. 113 Visage, Vila Leopoldina, S\u00e3o Paulo 05303-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano Marcondes Machado","family":"Nardozza","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Federal University of S\u00e3o Paulo (UNIFESP), Rua Carlos Weber, 956 apto. 113 Visage, Vila Leopoldina, S\u00e3o Paulo 05303-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Fernandes","family":"Moron","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Federal University of S\u00e3o Paulo (UNIFESP), Rua Carlos Weber, 956 apto. 113 Visage, Vila Leopoldina, S\u00e3o Paulo 05303-000, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2012000300009"},{"volume":"141, article w13325","journal-title":"Swiss Medical Weekly","year":"2012","key":"2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199903000-00013"},{"year":"2003","key":"4"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.127899"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.04.011"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1159\/000095670"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-006-0157-8"},{"issue":"5","key":"9","first-page":"890","volume":"78","year":"1991","journal-title":"Obstetrics and Gynecology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01367-9"},{"issue":"4","key":"11","doi-asserted-by":"crossref","first-page":"473","DOI":"10.7863\/jum.2011.30.4.473","volume":"30","year":"2011","journal-title":"Journal of Ultrasound in Medicine"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1086\/342108"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2012\/478436.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2012\/478436.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2012\/478436.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T19:07:25Z","timestamp":1497985645000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criid\/2012\/478436\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":12,"alternative-id":["478436","478436"],"URL":"https:\/\/doi.org\/10.1155\/2012\/478436","relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"type":"print","value":"2090-6625"},{"type":"electronic","value":"2090-6633"}],"subject":[],"published":{"date-parts":[[2012]]}}}