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Despite the excellent tumour control, conventional RT is associated with a potential risk of developing late toxicity, especially hypopituitarism, and its role in the management of patients with GH-secreting pituitary adenomas remains a matter of debate. Stereotactic techniques have been developed with the aim to deliver more localized irradiation and minimize the long-term consequences of treatment, while improving its efficacy. Stereotactic irradiation can be given in a single dose as stereotactic radiosurgery (SRS) or in multiple doses as fractionated stereotactic radiotherapy (FSRT). We have reviewed the recent published literature on stereotactic techniques for GH-secreting pituitary tumors with the aim to define the efficacy and potential adverse effects of each of these techniques.<\/jats:p>","DOI":"10.1155\/2012\/482861","type":"journal-article","created":{"date-parts":[[2012,2,22]],"date-time":"2012-02-22T16:02:35Z","timestamp":1329926555000},"page":"1-7","source":"Crossref","is-referenced-by-count":18,"title":["Stereotactic Irradiation of GH-Secreting Pituitary Adenomas"],"prefix":"10.1155","volume":"2012","author":[{"given":"G.","family":"Minniti","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Neuromed Institute, 86077 Pozzilli, Italy"},{"name":"Department of Radiation Oncology, Sant\u2019Andrea Hospital, University Sapienza, 00189 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Scaringi","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sant\u2019Andrea 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