{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T11:19:39Z","timestamp":1768994379662,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Transplantation"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Acute liver failure (ALF) during pregnancy is very uncommon. Pregnancy-specific liver conditions like hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome and acute fatty liver of pregnancy can cause ALF at term or postpartum, but, typically occur during the third trimester. Most of these patients recover spontaneously after delivery, but, on occasion, they require liver transplantation in the postpartum period. However, ALF during the first and second trimester of pregnancy requiring antepartum liver transplantation is rare. Only fifteen cases of liver transplantation during pregnancy have been reported, and very few occurred during the first trimester. We report a Woman who developed acute liver failure during the first trimester of pregnancy and underwent successful liver transplantation at 11-week gestation, followed by successful delivery of the fetus at 30 weeks. To our knowledge, this is the earliest case of successful liver transplantation during pregnancy followed by successful fetal outcome. We discuss management of the patient and fetus before, during, and after liver transplantation and review the literature on antepartum liver transplant in pregnancy.<\/jats:p>","DOI":"10.1155\/2012\/484080","type":"journal-article","created":{"date-parts":[[2012,11,26]],"date-time":"2012-11-26T16:08:34Z","timestamp":1353946114000},"page":"1-7","source":"Crossref","is-referenced-by-count":5,"title":["Liver Transplantation for Acute Liver Failure at 11-Week Gestation with Successful Maternal and Fetal Outcome"],"prefix":"10.1155","volume":"2012","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3049-4756","authenticated-orcid":true,"given":"Vinaya C.","family":"Maddukuri","sequence":"first","affiliation":[{"name":"Division of Hepatology, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney D.","family":"Stephenson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lon","family":"Eskind","sequence":"additional","affiliation":[{"name":"Department of Surgery, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Ahrens","sequence":"additional","affiliation":[{"name":"Department of Pathology, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preston","family":"Purdum","sequence":"additional","affiliation":[{"name":"Carolinas Digestive Health Associates, Charlotte, NC 28211, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark W.","family":"Russo","sequence":"additional","affiliation":[{"name":"Division of Hepatology, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203, USA"},{"name":"Transplant Center, Carolinas Medical Center, 3rd Floor Annex building, Charlotte, NC 28203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22130"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1073114"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2008.07.011"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21820"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2008.01871.x"},{"issue":"1","key":"6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/(SICI)1520-6661(199701\/02)6:1<40::AID-MFM8>3.3.CO;2-W","volume":"6","year":"1997","journal-title":"Journal of Maternal-Fetal and Neonatal Medicine"},{"issue":"12","key":"7","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1097\/00007890-200206270-00025","volume":"73","year":"2002","journal-title":"Transplantation"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199708150-00007"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2006.01246.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.02.090"},{"issue":"1, article 461","key":"11","volume":"5","year":"2011","journal-title":"Journal of Medical Case Reports"},{"issue":"1","key":"12","first-page":"24","volume":"8","year":"2006","journal-title":"AIDS Reviews"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22493"},{"issue":"5","key":"14","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1097\/00007890-199111000-00036","volume":"52","year":"1991","journal-title":"Transplantation"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800820811"},{"issue":"3","key":"16","first-page":"268","volume":"40","year":"2010","journal-title":"Acta Gastroenterologica Latinoamericana"},{"issue":"6","key":"17","first-page":"1083","volume":"76","year":"1990","journal-title":"Obstetrics and Gynecology"},{"issue":"3","key":"18","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/00007890-199009000-00041","volume":"50","year":"1990","journal-title":"Transplantation"},{"issue":"5","key":"19","first-page":"2967","volume":"25","year":"1993","journal-title":"Transplantation Proceedings"},{"key":"20","first-page":"311","year":"1989","journal-title":"Clinical Transplants"},{"issue":"5","key":"21","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/00007890-199509000-00019","volume":"60","year":"1995","journal-title":"Transplantation"},{"issue":"2","key":"22","doi-asserted-by":"crossref","first-page":"145","DOI":"10.7863\/jum.1994.13.2.145","volume":"13","year":"1994","journal-title":"Journal of Ultrasound in Medicine"}],"container-title":["Case Reports in Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2012\/484080.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2012\/484080.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2012\/484080.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T23:09:13Z","timestamp":1498000153000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crit\/2012\/484080\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":22,"alternative-id":["484080","484080"],"URL":"https:\/\/doi.org\/10.1155\/2012\/484080","relation":{},"ISSN":["2090-6943","2090-6951"],"issn-type":[{"value":"2090-6943","type":"print"},{"value":"2090-6951","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}