{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T10:43:44Z","timestamp":1753440224653},"reference-count":21,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Myeloid Sarcoma (MS), a rare extra hematopoietic carcinoma composed of blast cells, is located primarily in extramedullary sites such as skin, soft tissue, lymph nodes, and bone. MS usually presents in the setting of coexisting acute myeloid leukemia (AML) and myeloproliferative disorders. Gastrointestinal involvement (GI) is extremely rare from nonspecific abdominal symptoms to obstruction. Eight cases of myeloid sarcoma involving the duodenum including the current case have been reported, overall mean age being 40 years (range 17\u201371) and M\u2009:\u2009F ratio 7\u2009:\u20091. The prognosis of patients with<jats:italic>de novo<\/jats:italic>MS cases has been reported to be better than those who have a coexisting leukemia. MS is a rare extramedullary tumor, which should be considered in the differential diagnosis of a soft tissue mass involving the duodenum, especially if there is a coexisting hematological disorder.<jats:italic>De novo<\/jats:italic>cases often progress to AML, and current therapy involves Daunorubicin- and Cytarabine-based chemotherapy. The wide cytogenetic and molecular heterogeneity of MS implies a potential role for more targeted MS therapies, which may offer a curative strategy.<\/jats:p>","DOI":"10.1155\/2012\/490438","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T16:25:12Z","timestamp":1354206312000},"page":"1-7","source":"Crossref","is-referenced-by-count":9,"title":["Primary Myeloid Sarcoma Masquerading as an Obstructing Duodenal Carcinoma"],"prefix":"10.1155","volume":"2012","author":[{"given":"Preeti","family":"Narayan","sequence":"first","affiliation":[{"name":"School of Medicine, St. George\u2019s University, Grenada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijayashree","family":"Murthy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mu","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Pathology, Saint Barnabas Medical Center, Livingston, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemonde","family":"Woel","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Saint Barnabas Medical Center, Livingston, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. 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