{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T06:48:28Z","timestamp":1759042108759},"reference-count":7,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Psychiatry"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Tourette syndrome (TS) is a neurodevelopmental disorder with chronic and disabling impacts on multiple domains of functioning in children. Treatment of TS is often complicated by comorbid conditions. We present a 12-year-old boy with severe symptoms of Tourette syndrome (TS), with prominent and markedly disabling vocal tics, who failed to respond to substantial doses of risperidone and haloperidol, given for a prolonged period. Satisfactory outcome was achieved with exposure and response prevention, adjunct to medication. Comorbid ADHD was treated with stimulants with no exacerbation of tics.<\/jats:p>","DOI":"10.1155\/2012\/497160","type":"journal-article","created":{"date-parts":[[2012,9,23]],"date-time":"2012-09-23T21:00:28Z","timestamp":1348434028000},"page":"1-3","source":"Crossref","is-referenced-by-count":2,"title":["Management of Severe Pediatric Tourette Syndrome Resistant to Drug Treatment"],"prefix":"10.1155","volume":"2012","author":[{"given":"Hemamali","family":"Perera","sequence":"first","affiliation":[{"name":"University Psychological Medicine Unit, Lady Ridgeway Hospital for Children, Colombo 08, Sri Lanka"},{"name":"Department of Psychological Medicine, Faculty of Medicine, University of Colombo, Kinsey Road, Colombo 08, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chittahari","family":"Abayanayaka","sequence":"additional","affiliation":[{"name":"University Psychological Medicine Unit, Lady Ridgeway Hospital for Children, Colombo 08, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","year":"2000"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1177\/1756285610390261"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162200000839"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10618"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1177\/0145445507309020"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21577"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1981.01780350118016"}],"container-title":["Case Reports in Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crips\/2012\/497160.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crips\/2012\/497160.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crips\/2012\/497160.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T19:15:13Z","timestamp":1470165313000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crips\/2012\/497160\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":7,"alternative-id":["497160","497160"],"URL":"https:\/\/doi.org\/10.1155\/2012\/497160","relation":{},"ISSN":["2090-682X","2090-6838"],"issn-type":[{"value":"2090-682X","type":"print"},{"value":"2090-6838","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}