{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:27:51Z","timestamp":1770884871805,"version":"3.50.1"},"reference-count":58,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,10,31]],"date-time":"2012-10-31T00:00:00Z","timestamp":1351641600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thrombosis"],"published-print":{"date-parts":[[2012,10,31]]},"abstract":"<jats:p>Postthrombotic syndrome \n(PTS) is a late outcome of deep vein thrombosis characterized by \ncramping pain, swelling, hyperpigmentation, eczema, \nlipodermatosclerosis, and ulceration in the leg due to increased \nvenous outflow resistance and  reflux venous flow. Newer surgical \nand endovascular interventions have a promising result in the \nmanagement of postthrombotic syndrome. Early surgical or \nendovascular interventions in appropriately selected patients may \ndecrease the incidence of recurrent ulceration and skin changes and \nprovide a better quality of life. Duplex and IVUS (intravenous \nultrasound) along with venography serve as cornerstone \ninvestigative tools for assessment of reflux and obstruction. \nVenous obstruction, if present, should be addressed earlier than \nreflux. It requires endovenous stenting, endophlebectomy, or open \nbypass procedures. Venous stripping, foam sclerotherapy, \nradiofrequency, or laser ablation are used to abolish superficial \nvenous reflux. Valvuloplasty procedures are useful for incompetent \nbut intact deep venous valves, while transposition or axillary \nvein autotransplantation is done for completely destroyed \nvalves.<\/jats:p>","DOI":"10.1155\/2012\/520604","type":"journal-article","created":{"date-parts":[[2011,10,31]],"date-time":"2011-10-31T19:01:08Z","timestamp":1320087668000},"page":"1-7","source":"Crossref","is-referenced-by-count":24,"title":["Postthrombotic Syndrome: Surgical Possibilities"],"prefix":"10.1155","volume":"2012","author":[{"given":"Ajay K.","family":"Khanna","sequence":"first","affiliation":[{"name":"Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-1172","authenticated-orcid":true,"given":"Shivanshu","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Institute of Medical Sciences, Banaras 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