{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T17:29:10Z","timestamp":1791134950567,"version":"4.1.0"},"reference-count":24,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Pediatrics"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>: To study the outcome of disconnective epilepsy surgery for intractable hemispheric and sub-hemispheric pediatric epilepsy.<jats:italic>Methods<\/jats:italic>: A retrospective analysis of the epilepsy surgery database was done in all children (age &lt;18 years) who underwent a peri-insular hemispherotomy (PIH) or a peri-insular posterior quadrantectomy (PIPQ) from April 2000 to March 2011. All patients underwent a detailed pre surgical evaluation. Seizure outcome was assessed by the Engel\u2019s classification and cognitive skills by appropriate measures of intelligence that were repeated annually.<jats:italic>Results<\/jats:italic>: There were 34 patients in all. Epilepsy was due to Rasmussen\u2019s encephalitis (RE), Infantile hemiplegia seizure syndrome (IHSS), Hemimegalencephaly (HM), Sturge Weber syndrome (SWS) and due to post encephalitic sequelae (PES). Twenty seven (79.4%) patients underwent PIH and seven (20.6%) underwent PIPQ. The mean follow up was 30.5 months. At the last follow up, 31 (91.1%) were seizure free. The age of seizure onset and etiology of the disease causing epilepsy were predictors of a Class I seizure outcome.<jats:italic>Conclusions<\/jats:italic>: There is an excellent seizure outcome following disconnective epilepsy surgery for intractable hemispheric and subhemispheric pediatric epilepsy. An older age of seizure onset, RE, SWS and PES were good predictors of a Class I seizure outcome.<\/jats:p>","DOI":"10.1155\/2012\/527891","type":"journal-article","created":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T21:03:34Z","timestamp":1328821414000},"page":"1-7","source":"Crossref","is-referenced-by-count":23,"title":["Outcomes of Disconnective Surgery in Intractable Pediatric Hemispheric and Subhemispheric Epilepsy"],"prefix":"10.1155","volume":"2012","author":[{"given":"Santhosh George","family":"Thomas","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Department of Neurological Sciences, Christian Medical College, Vellore 632004, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari George","family":"Chacko","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Neurological Sciences, Christian Medical College, Vellore 632004, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya Mary","family":"Thomas","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Department of Neurological Sciences, Christian Medical College, Vellore 632004, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Srinivasa","family":"Babu","sequence":"additional","affiliation":[{"name":"Division of Neurophysiology, Department of Neurological Sciences, Christian Medical College, Vellore 632004, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul Swamidhas Sudhakar","family":"Russell","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Christian Medical College, Vellore 632004, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy Thomas","family":"Daniel","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Clinical Neurosciences, CHUV, Rue du Bugnon 46, 1011 Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","first-page":"1813","volume-title":"Seizures in childhood","year":"2000"},{"issue":"8","key":"2","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/j.1528-1157.2000.tb00289.x","volume":"41","year":"2000","journal-title":"Epilepsia"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.43.s.3.6.x"},{"issue":"4","key":"4","first-page":"263","volume":"44","year":"2007","journal-title":"Indian Pediatrics"},{"issue":"30","key":"5","first-page":"1597","volume":"142","year":"2001","journal-title":"Orvosi Hetilap"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01095.x"},{"key":"7","first-page":"196","volume-title":"Posterior Quadrantic Resection and Disconnection","year":"2008"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-006-0212-6"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-006-0134-3"},{"issue":"4","key":"15","first-page":"891","volume":"49","year":"2001","journal-title":"Neurosurgery"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000249246.48299.12"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-010-1102-5"},{"issue":"4","key":"10","first-page":"263","volume":"44","year":"2007","journal-title":"Indian Pediatrics"},{"key":"11","first-page":"52","volume":"20","year":"2003","journal-title":"Epileptologie"},{"issue":"5","key":"12","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1227\/00006123-199511000-00018","volume":"37","year":"1995","journal-title":"Neurosurgery"},{"issue":"1","key":"16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1159\/000028896","volume":"32","year":"2000","journal-title":"Pediatric Neurosurgery"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg052"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh224"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.53704.x"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.461009.x"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2006.00909.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1111\/j.0013-9580.2005.03504.x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.76854"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2001.12200.x"}],"container-title":["International Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijpedi\/2012\/527891.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijpedi\/2012\/527891.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijpedi\/2012\/527891.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T14:00:45Z","timestamp":1497967245000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijpedi\/2012\/527891\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":24,"alternative-id":["527891","527891"],"URL":"https:\/\/doi.org\/10.1155\/2012\/527891","relation":{},"ISSN":["1687-9740","1687-9759"],"issn-type":[{"value":"1687-9740","type":"print"},{"value":"1687-9759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}