{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:03:09Z","timestamp":1761580989039},"reference-count":33,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advances in Urology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. We analyzed radical TUR-PCa against localized prostate cancer.<jats:italic>Patients and Methods<\/jats:italic>. Seventy-nine out of 209 patients with prostate cancer in one lobe were studied. Patients\u2019 age ranged from 58 to 91 years and preoperative PSA, 0.70 to 17.30\u2009ng\/mL. In other 16 additional patients we performed focal TUR-PCa. Patients\u2019 age ranged from 51 to 87 years and preoperative PSA, 1.51 to 25.74\u2009ng\/mL.<jats:italic>Results<\/jats:italic>. PSA failure in radical TUR-PCa was 5.1% during the mean follow-up period of 58.9 months. The actuarial biochemical non-recurrence rate was 98.2% for pT2a and 90.5% for pT2b. Bladder neck contracture occurred in 28 patients (35.4%). In 209 patients, pathological study revealed prostate cancer of the peripheral zone near the neurovascular bundle bilaterally in 25%, unilaterally in 39% and no cancer bilaterally in 35%, suggesting the possibility of focal TUR-PCa. Postoperative PSA of 16 patients treated by focal TUR-PCa was stable between 0.007 and 0.406\u2009ng\/mL at 24.2 months\u2019 follow-up. No patients suffered from urinary incontinence. Bladder neck contracture developed in only 1 patient and all 5 patients underwent nerve-preserving TUR-PCa did not show erectile dysfunction.<jats:italic>Conclusion<\/jats:italic>. Focal TUR-PCa was considered to be a promising option among focal therapies against localized prostate cancer.<\/jats:p>","DOI":"10.1155\/2012\/564372","type":"journal-article","created":{"date-parts":[[2012,5,29]],"date-time":"2012-05-29T07:11:20Z","timestamp":1338275480000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Management of Localized Prostate Cancer by Focal Transurethral Resection of Prostate Cancer: An Application of Radical TUR-PCa to Focal Therapy"],"prefix":"10.1155","volume":"2012","author":[{"given":"Masaru","family":"Morita","sequence":"first","affiliation":[{"name":"Department of Urology, Kounaizaka Clinic, 1917-3 Asakura-Hei, Kochi 780-8063, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Department of Urology, Matsubara Tokushukai Hospital, 7-13-26 Amami-Higashi, Matsubara, Osaka 580-0032, 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