{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T15:17:13Z","timestamp":1767626233297,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Critical Care Research and Practice"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. We evaluated whether routine ultrasound examination may illustrate gallbladder abnormalities, including acute acalculous cholecystitis (AAC) in the intensive care unit (ICU).<jats:italic>Patients and Methods<\/jats:italic>. Ultrasound monitoring of the GB was performed by two blinded radiologists in mechanically ventilated patients irrespective of clinical and laboratory findings. We evaluated major (gallbladder wall thickening and edema, sonographic Murphy\u2019s sign, pericholecystic fluid) and minor (gallbladder distention and sludge) ultrasound criteria.<jats:italic>Measurements and Results<\/jats:italic>. We included 53 patients (42 males; mean age<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn>57.6<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>2.8<\/mml:mn><\/mml:math>years; APACHE II score<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn>21.3<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.9<\/mml:mn><\/mml:math>; mean ICU stay<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn>35.9<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>4.8<\/mml:mn><\/mml:math>days). Twenty-five patients (47.2%) exhibited at least one abnormal imaging finding, while only six out of them had hepatic dysfunction. No correlation existed between liver biochemistry and ultrasound results in the total population. Three male patients (5.7%), on the grounds of unexplained sepsis, were diagnosed with AAC as incited by ultrasound, and surgical intervention was lifesaving. Patients who exhibited \u22652 ultrasound findings (30.2%) were managed successfully under the guidance of evolving ultrasound, clinical, and laboratory findings.<jats:italic>Conclusions<\/jats:italic>. Ultrasound gallbladder monitoring guided lifesaving surgical treatment in 3 cases of AAC; however, its routine application is questionable and still entails high levels of clinical suspicion.<\/jats:p>","DOI":"10.1155\/2012\/565617","type":"journal-article","created":{"date-parts":[[2012,5,9]],"date-time":"2012-05-09T17:04:05Z","timestamp":1336583045000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["Is Routine Ultrasound Examination of the Gallbladder Justified in Critical Care Patients?"],"prefix":"10.1155","volume":"2012","author":[{"given":"Pavlos","family":"Myrianthefs","sequence":"first","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"},{"name":"Department of Intensive Care Unit, General State Hospital of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efimia","family":"Evodia","sequence":"additional","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioanna","family":"Vlachou","sequence":"additional","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glykeria","family":"Petrocheilou","sequence":"additional","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Gavala","sequence":"additional","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Pappa","sequence":"additional","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Baltopoulos","sequence":"additional","affiliation":[{"name":"Department of Intensive Care at \u201cAgioi Anargyroi\u201d General Hospital, Faculty of Nursing, University of Athens, Kaliftaki, 14564 Nea Kifissia, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Karakitsos","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, General State Hospital of Athens, Athens, 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