{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T18:24:25Z","timestamp":1648578265101},"reference-count":22,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Vascular Medicine"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>To examine if mild carotid stenosis correlates with silent vascular brain changes, we studied a prospective population-based cohort \u201cMen born in 1914.\u201d Data from followups at ages 68 and 81, have been used. Carotid ultrasound was performed at age 81, and cerebral blood flow (CBF) was measured with SPECT at age 82. Out of 123 stroke-free patients, carotid stenosis &lt;50% was observed in 94% in the right and 89% in the left internal carotid arteries (ICAs). In these subjects, Peak Systolic Velocities in ICA correlated negatively with CBF in a majority of several brain areas, especially in mesial temporal area. Results were limited to normotensive until their seventies, who developed late-onset hypertension with a subsequent blood pressure, pulse pressure, and ankle-brachial index growth. Elderly with asymptomatic carotid stenosis &lt;50% and peak systolic velocities in ICA 0.7\u20131.3\u2009m\/s, should be offered an intensified pharmacotherapy to prevent stroke or silent cerebrovascular events.<\/jats:p>","DOI":"10.1155\/2012\/579531","type":"journal-article","created":{"date-parts":[[2012,6,19]],"date-time":"2012-06-19T21:04:35Z","timestamp":1340139875000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis &lt;50%"],"prefix":"10.1155","volume":"2012","author":[{"given":"Arkadiusz","family":"Siennicki-Lantz","sequence":"first","affiliation":[{"name":"Division of Geriatric Medicine, Department of Health Sciences, Skane University Hospital in Malm\u00f6, Lund University, 205 02 Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Wollmer","sequence":"additional","affiliation":[{"name":"Unit of Clinical Physiology and Nuclear Medicine, Department of Clinical Sciences, Skane University Hospital in Malm\u00f6, Lund University, 205 02 Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f6lve","family":"Elmst\u00e5hl","sequence":"additional","affiliation":[{"name":"Division of Geriatric Medicine, Department of Health Sciences, Skane University Hospital in Malm\u00f6, Lund University, 205 02 Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301283280401"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.273.18.1421"},{"issue":"9420","key":"3","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/S0140-6736(04)16146-1","volume":"363","year":"2004","journal-title":"The Lancet"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2011.05.015"},{"issue":"4","key":"5","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.jvs.2008.10.059","volume":"49","year":"2009","journal-title":"Journal of Vascular Surgery"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2004.09.024"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2292030516"},{"issue":"1","key":"8","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1148\/radiology.220.1.r01jl33174","volume":"220","year":"2001","journal-title":"Radiology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1177\/0003319708325447"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2004.09.001"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20351"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.489807"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5884(96)80252-8"},{"issue":"6990","key":"14","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1136\/bmj.310.6990.1294","volume":"310","year":"1995","journal-title":"British Medical Journal"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2007.01805.x"},{"issue":"2","key":"16","first-page":"103","volume":"99","year":"1994","journal-title":"Italian Journal of Anatomy and Embryology"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.09.047"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(00)00293-3"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)92123-B"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20332"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/417291"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-11-57"}],"container-title":["International Journal of Vascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijvm\/2012\/579531.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijvm\/2012\/579531.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijvm\/2012\/579531.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T20:18:24Z","timestamp":1497989904000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijvm\/2012\/579531\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":22,"alternative-id":["579531","579531"],"URL":"https:\/\/doi.org\/10.1155\/2012\/579531","relation":{},"ISSN":["2090-2824","2090-2832"],"issn-type":[{"value":"2090-2824","type":"print"},{"value":"2090-2832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}