{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:12:32Z","timestamp":1771017152129,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Orthopedics"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Nutritional deficiencies are rarely reported in developed countries. We report a child of Pakistani origin brought up in Dubai who developed skeletal manifestations of scurvy due to peculiar dietary habits.<jats:italic>Case Presentation<\/jats:italic>. A 4.5 year old boy presented with pain and swelling of multiple joints for three months and inability to walk for two months. Dietary history was significant for exclusive meat intake for the preceding two years. On examination the child\u2019s height and weight were below the 5th percentile for his age. He was pale and tachycardic. There was significant swelling and tenderness over the wrist, knee and ankle joints, along with painful restriction of motion. Basic blood workup was unremarkable except for anemia. However, X-rays showed delayed bone age, severe osteopenia of the long bones, epiphyseal separation, cortical thinning and dense zone of provisional calcification, suggesting a radiological diagnosis of scurvy. The child was started on vitamin C replacement therapy. Over the following two months, the pain and swelling substantially reduced and the child became able to walk. Repeat X-rays showed improvement in the bony abnormalities.<jats:italic>Conclusion<\/jats:italic>. Although scurvy is not a very commonly encountered entity in the modern era, inappropriate dietary intake can lead to skeletal abnormalities which may be confused with rickets. A high index of suspicion is thus required for prompt diagnosis of scurvy in patients with bone and joint symptoms.<\/jats:p>","DOI":"10.1155\/2012\/624628","type":"journal-article","created":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T17:00:12Z","timestamp":1346691612000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["Skeletal Manifestations of Scurvy: A Case Report from Dubai"],"prefix":"10.1155","volume":"2012","author":[{"given":"Shahryar","family":"Noordin","sequence":"first","affiliation":[{"name":"Department of Surgery, Section of Orthopaedics, Aga Khan University, P.O. Box 3500, Stadium Road, Karachi 74800, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2870-781X","authenticated-orcid":true,"given":"Naveed","family":"Baloch","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Orthopaedics, Aga Khan University, P.O. Box 3500, Stadium Road, Karachi 74800, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Sohail","family":"Salat","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health, Aga Khan University, Karachi 74800, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul","family":"Rashid Memon","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health, Aga Khan University, Karachi 74800, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tashfeen","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Surgery, Section of Orthopaedics, Aga Khan University, P.O. Box 3500, Stadium Road, Karachi 74800, Pakistan"},{"name":"Department of Biological and Biomedical Sciences, Section of Anatomy, Aga Khan University, Karachi 74800, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"3","key":"2","first-page":"198","volume":"19","year":"2009","journal-title":"Journal of the College of Physicians and Surgeons Pakistan"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4103\/0256-4947.65266"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1258\/td.2009.080447"},{"key":"5","first-page":"S734","volume":"86","year":"2003","journal-title":"Journal of the Medical Association of Thailand"},{"issue":"5","key":"6","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1001\/archpedi.155.5.607","volume":"155","year":"2001","journal-title":"Archives of Pediatrics and Adolescent Medicine"},{"key":"7","volume-title":"Metabolic bone diseases","year":"2004"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-003-0735-9"},{"key":"9","volume-title":"Musculoskeletal system","year":"1998"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc079017"},{"issue":"3","key":"11","doi-asserted-by":"crossref","first-page":"E55","DOI":"10.1542\/peds.108.3.e55","volume":"108","year":"2001","journal-title":"Pediatrics"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2004.01.007"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2005.01.018"},{"issue":"4","key":"14","first-page":"314","volume":"14","year":"2001","journal-title":"Journal of the American Board of Family Practice"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.8.3704"}],"container-title":["Case Reports in Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crior\/2012\/624628.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crior\/2012\/624628.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crior\/2012\/624628.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T19:36:16Z","timestamp":1497987376000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crior\/2012\/624628\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":14,"alternative-id":["624628","624628"],"URL":"https:\/\/doi.org\/10.1155\/2012\/624628","relation":{},"ISSN":["2090-6749","2090-6757"],"issn-type":[{"value":"2090-6749","type":"print"},{"value":"2090-6757","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}