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The chronic bacterial infections are characterized by being a large bacterial infection and\/or an infection where the bacteria grows rapidly. In these cases, the immune response is not capable of completely eliminating the infection which may lead to the formation of a pattern known as microabscess (or abscess). The microabscess is characterized by an area comprising fluids, bacteria, immune cells (mainly neutrophils), and many types of dead cells. This distinct pattern of formation can only be numerically reproduced and studied by models that capture the spatiotemporal dynamics of the human immune system (HIS). In this context, our work aims to develop and implement an initial computational model to study the process of microabscess formation during a bacterial infection.<\/jats:p>","DOI":"10.1155\/2012\/736394","type":"journal-article","created":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T21:08:42Z","timestamp":1352408922000},"page":"1-16","source":"Crossref","is-referenced-by-count":15,"title":["Computational Modeling of Microabscess Formation"],"prefix":"10.1155","volume":"2012","author":[{"given":"Alexandre Bittencourt","family":"Pigozzo","sequence":"first","affiliation":[{"name":"Graduate Program in Computational Modeling, UFJF, Rua Jos\u00e9 Louren\u00e7o Kelmer s\/n, Campus Universit\u00e1rio, Bairro S\u00e3o Pedro, 36036-900 Juiz de Fora, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilson Costa","family":"Macedo","sequence":"additional","affiliation":[{"name":"Graduate Program in Biological Sciences, UFJF, Rua Jos\u00e9 Louren\u00e7o Kelmer 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