{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:24:05Z","timestamp":1778574245751,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Inflammation"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Medical and microbiology records of seventeen patients (17 eyes), diagnosed as scleritis of infectious origin were reviewed; to study clinical features, predisposing risk factors, microbiologic profile and treatment outcome of infectious scleritis. The mean patient age was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>52.3<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>19.75<\/mml:mn><\/mml:mrow><\/mml:math>years. Twelve patients (70.6%) had history of trauma\/prior surgery. Isolated organisms included<jats:italic>Staphylococcus<\/jats:italic>species (spp)<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>5<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:math>, Fungus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>4<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:math>,<jats:italic>Nocardia<\/jats:italic>spp<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>3<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:math>, two each of atypical<jats:italic>Mycobacterium<\/jats:italic>spp and<jats:italic>Streptococcus pneumoniae<\/jats:italic>and one<jats:italic>Pseudomonas aeruginosa<\/jats:italic>. Treatment included intensive topical antimicrobial in all eyes and systemic medication in 15\u2009(88.2%) patients; surgical exploration was needed for 13\u2009(76.5%) patients and scleral patch graft was done in four (23.5%) patients. Lesions resolved in all patients and none required evisceration. The presenting log MAR visual acuity of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>1.77<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>1.40<\/mml:mn><\/mml:mrow><\/mml:math>and improved to<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>0.99<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.91<\/mml:mn><\/mml:mrow><\/mml:math>.<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>P<\/mml:mi><mml:mo>\u2264<\/mml:mo><mml:mn>0.039<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:math>after treatment with a mean follow up of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>22.57<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>19.53<\/mml:mn><\/mml:mrow><\/mml:math>weeks. A microbiological confirmation, appropriate medical and\/or surgical intervention has a good tectonic and visual outcome.<\/jats:p>","DOI":"10.1155\/2012\/753560","type":"journal-article","created":{"date-parts":[[2011,11,20]],"date-time":"2011-11-20T16:01:07Z","timestamp":1321804867000},"page":"1-8","source":"Crossref","is-referenced-by-count":18,"title":["Clinico-Microbiological Profile and Treatment Outcome of Infectious Scleritis: Experience from a Tertiary Eye Care Center of India"],"prefix":"10.1155","volume":"2012","author":[{"given":"Srikant","family":"Kumar Sahu","sequence":"first","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar 751024, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujata","family":"Das","sequence":"additional","affiliation":[{"name":"Cornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar 751024, 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