{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:39:18Z","timestamp":1761561558092},"reference-count":34,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Xinjiang Uygur Autonomic Tackle Key Problems Plans","award":["200633129","200733146-2"],"award-info":[{"award-number":["200633129","200733146-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Diabetes Research"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Background and Aims<\/jats:italic>. This study was designed to explore the relationship between periodontitis and diabetes mellitus (DM) in Uygur adults from Xinjiang.<jats:italic>Methods and Results<\/jats:italic>. Data were obtained using questionnaire and oral examination. Participants (48.87 \u00b113.72 yr) were categorized into periodontitis and non-periodontitis groups in accordance with the chronic periodontitis diagnostic criteria. Based on gum inflammation, bleeding on probing, periodontal pocket depth and attachment loss, patients were further divided into mild, moderate and severe periodontitis groups. Among 962 subjects, 453 (47.1%) suffered from chronic periodontitis with a prevalence of type 2 DM and impaired fasting glucose of 9.5% and 11.4%, respectively. In the periodontitis group, the prevalence of type 2 DM was 75.6% compared with 22.4% in the non-periodontitis group. Likewise, the prevalence of impaired fasting glucose was 71.3% and 28.7% in periodontitis and non-periodontitis groups, respectively. The univariate logistic regression analysis revealed moderate and severe periodontitis as risk factors for DM (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>OR<\/mml:mtext><mml:mo>=<\/mml:mo><mml:mn>3.4<\/mml:mn><\/mml:mrow><\/mml:math>,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>OR<\/mml:mtext><mml:mo>=<\/mml:mo><mml:mn>2.9<\/mml:mn><\/mml:mrow><\/mml:math>). Multivariate logistic regression analysis showed that moderate periodontitis is independently associated with DM (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>OR<\/mml:mtext><mml:mo>=<\/mml:mo><mml:mn>4<\/mml:mn><\/mml:mrow><\/mml:math>).<jats:italic>Conclusions<\/jats:italic>. Our data revealed that prevalence of DM is overtly higher in periodontitis patients than in individuals without periodontitis. Furthermore, moderate periodontitis is considered an independent risk factor for type 2 DM.<\/jats:p>","DOI":"10.1155\/2012\/758921","type":"journal-article","created":{"date-parts":[[2011,8,2]],"date-time":"2011-08-02T15:00:51Z","timestamp":1312297251000},"page":"1-7","source":"Crossref","is-referenced-by-count":18,"title":["Epidemiological Survey on the Prevalence of Periodontitis and Diabetes Mellitus in Uyghur Adults from Rural Hotan Area in Xinjiang"],"prefix":"10.1155","volume":"2012","author":[{"given":"Gulinuer","family":"Awuti","sequence":"first","affiliation":[{"name":"Department of Stomatology, the First Affiliated Hospital, Xinjiang Medical University, Xinjiang 830011, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurexi","family":"Younusi","sequence":"additional","affiliation":[{"name":"Xinjiang Medical University, Xinjiang 830011, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linlin","family":"Li","sequence":"additional","affiliation":[{"name":"Xinjiang Medical University, Xinjiang 830011, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halmurat","family":"Upur","sequence":"additional","affiliation":[{"name":"Xinjiang Medical University, Xinjiang 830011, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ren","sequence":"additional","affiliation":[{"name":"Xinjiang Medical University, Xinjiang 830011, China"},{"name":"College of Health Sciences, University of Wyoming, Laramie, WY 82071, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-008-0079-y"},{"issue":"2","key":"3","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1385\/ENDO:25:2:073","volume":"25","year":"2004","journal-title":"Endocrine"},{"issue":"4","key":"4","first-page":"234","volume":"11","year":"2009","journal-title":"Journal of the International Academy of Periodontology"},{"key":"5","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1111\/j.1834-7819.2009.01140.x","volume":"54","year":"2009","journal-title":"Australian Dental Journal"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2010.00353.x"},{"key":"7","first-page":"33","volume":"32","year":"2009","journal-title":"Odontostomatol Trop"},{"key":"8"},{"key":"9","first-page":"698","volume":"16","year":"2006","journal-title":"Chinese Journal of Conservative Dentistry"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.19.2560"},{"key":"11","year":"2002"},{"key":"12","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.2337\/dc07-S042","volume":"30","year":"2007","journal-title":"Diabetes Care"},{"key":"14","year":"2003"},{"key":"15","first-page":"156","volume":"12","year":"2004","journal-title":"Chinese Journal of Diabetes"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.109.863779"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1126\/science.1115535"},{"key":"18","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1177\/002203459607502S07","volume":"75","year":"1996","journal-title":"Journal of Dental Research"},{"issue":"1","key":"19","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1902\/annals.2001.6.1.99","volume":"6","year":"2001","journal-title":"Annals of periodontology"},{"issue":"1","key":"20","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1902\/annals.1998.3.1.51","volume":"3","year":"1998","journal-title":"Annals of Periodontology"},{"issue":"1","key":"21","doi-asserted-by":"crossref","first-page":"329","DOI":"10.2337\/diacare.16.1.329","volume":"16","year":"1993","journal-title":"Diabetes Care"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1177\/154405910508401010"},{"issue":"5","key":"24","doi-asserted-by":"crossref","first-page":"S534","DOI":"10.1016\/S0002-8703(99)70294-2","volume":"138","year":"1999","journal-title":"American Heart Journal"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2003.10.007"},{"issue":"4","key":"26","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1210\/jcem-58-4-710","volume":"58","year":"1984","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"issue":"4","key":"27","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3109\/00365528309181638","volume":"18","year":"1983","journal-title":"Scandinavian Journal of Gastroenterology"},{"issue":"1","key":"28","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-2796.1989.tb00030.x","volume":"225","year":"1989","journal-title":"Journal of Internal Medicine"},{"issue":"10","key":"29","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/0026-0495(87)90128-4","volume":"36","year":"1987","journal-title":"Metabolism"},{"key":"30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2337\/diab.41.2.S97","volume":"41","year":"1992","journal-title":"Diabetes"},{"issue":"1","key":"31","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1210\/endo-127-1-46","volume":"127","year":"1990","journal-title":"Endocrinology"},{"issue":"5091","key":"32","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1126\/science.7678183","volume":"259","year":"1993","journal-title":"Science"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1038\/39335"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1177\/154405910508400911"},{"key":"35","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.2741\/3812","volume":"16","year":"2011","journal-title":"Frontiers in Bioscience"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-010-0116-4"},{"key":"37","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/j.1751-7176.2010.00349.x","volume":"12","year":"2010","journal-title":"The Journal of Clinical Hypertension"}],"container-title":["Experimental Diabetes Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2012\/758921.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2012\/758921.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2012\/758921.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T13:51:56Z","timestamp":1560433916000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/jdr\/2012\/758921\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":34,"alternative-id":["758921","758921"],"URL":"https:\/\/doi.org\/10.1155\/2012\/758921","relation":{},"ISSN":["1687-5214","1687-5303"],"issn-type":[{"value":"1687-5214","type":"print"},{"value":"1687-5303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}