{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T19:15:30Z","timestamp":1770146130257,"version":"3.49.0"},"reference-count":12,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. Over a period of three years, several different treatment regimens including liposomal amphotericin B, liposomal amphotericin B with miltefosine, liposomal amphotericin B with interferon, and pentamidine combined fluconazole and allopurinol were applied until Leishmania PCR from blood turned negative. This case supports the necessity of multidrug combinational and sequential therapy over a very prolonged period of time in severely immunosuppressed patients infected with Leishmania and highlights the tremendous individual but also economic burden of this disease.<\/jats:p>","DOI":"10.1155\/2012\/787305","type":"journal-article","created":{"date-parts":[[2012,12,17]],"date-time":"2012-12-17T21:21:43Z","timestamp":1355779303000},"page":"1-3","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Challenges in the Management of Leishmania\/HIV Coinfection in a Nonendemic Area: A Case Report"],"prefix":"10.1155","volume":"2012","author":[{"given":"K.","family":"Grabmeier-Pfistershammer","sequence":"first","affiliation":[{"name":"Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Poeppl","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Tropical Medicine, Medical University of Vienna, 1090 Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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