{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T21:19:55Z","timestamp":1721164795055},"reference-count":19,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>A 71-year-old man was diagnosed with an aggressive mantle cell lymphoma and was started on six cycles of R-CHOP chemotherapy. Approximately two weeks after starting his first cycle of chemotherapy, he complained of severe right lower quadrant abdominal pain, and an abdominal CT scan demonstrated an enlarged appendix with evidence of contained perforation. The man underwent open appendectomy for acute appendicitis and recovered. The appendectomy specimen was submitted for routine pathological analysis. There was histologic evidence of perforation in association with an inflammatory infiltrate with fibrin adhered to the serosal surface; scattered small lymphoid aggregates were present on the mucosal surface. Although the lymphoid aggregates in the submucosa and lamina propria were rather unremarkable by routine histologic examination, immunohistochemistry revealed the lymphocytes to be predominantly Cyclin D1-overexpressing B cells. To our knowledge, this is the first reported case of acute appendicitis in association with appendiceal involvement by mantle cell lymphoma.<\/jats:p>","DOI":"10.1155\/2012\/868151","type":"journal-article","created":{"date-parts":[[2012,3,29]],"date-time":"2012-03-29T21:02:50Z","timestamp":1333054970000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Acute Appendicitis in a Man Undergoing Therapy for Mantle Cell Lymphoma"],"prefix":"10.1155","volume":"2012","author":[{"given":"Michael","family":"Linden","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, University of Minnesota, MMC 806, Minneapolis, MN 55455, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay","family":"Gopal","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Washington, Seattle, WA 98195, USA"},{"name":"Seattle Cancer Care Alliance, Seattle, WA 98109, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Edlefsen","sequence":"additional","affiliation":[{"name":"Seattle Cancer Care Alliance, Seattle, WA 98109, USA"},{"name":"Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"8","key":"1","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1177\/000313481007600822","volume":"76","year":"2010","journal-title":"The American Surgeon"},{"issue":"5","key":"2","doi-asserted-by":"crossref","first-page":"E87","DOI":"10.1177\/000313481107700503","volume":"77","year":"2011","journal-title":"The American Surgeon"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4103\/0189-6725.70433"},{"key":"4","volume":"451, article 444","year":"2007","journal-title":"Virchows Archiv"},{"issue":"12","key":"5","first-page":"629","volume":"67","year":"2004","journal-title":"Journal of the Chinese Medical Association"},{"issue":"4","key":"6","first-page":"311","volume":"39","year":"1984","journal-title":"Medical Journal of Malaysia"},{"issue":"4","key":"7","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1046\/j.1365-2559.1999.0669e.x","volume":"34","year":"1999","journal-title":"Histopathology"},{"key":"8","first-page":"S146","volume":"101","year":"2006","journal-title":"American Journal of Gastroenterology"},{"issue":"4","key":"9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.5858\/1999-123-0335-AILCLO","volume":"123","year":"1999","journal-title":"Archives of Pathology and Laboratory Medicine"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s004320050105"},{"issue":"11","key":"11","first-page":"1352","volume":"118","year":"1983","journal-title":"Archives of Surgery"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-5-5"},{"key":"13","volume":"114","year":"1998","journal-title":"Gastroenterology"},{"issue":"1","key":"14","first-page":"79","volume":"16","year":"2006","journal-title":"Journal of the College of Physicians and Surgeons"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-6646(10)60080-0"},{"key":"16","year":"2008"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2010.532893"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2005.02225.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-008-0621-x"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2012\/868151.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2012\/868151.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2012\/868151.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T11:01:40Z","timestamp":1713783700000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crihem\/2012\/868151\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":19,"alternative-id":["868151","868151"],"URL":"https:\/\/doi.org\/10.1155\/2012\/868151","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"value":"2090-6560","type":"print"},{"value":"2090-6579","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}