{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:41:32Z","timestamp":1767908492259,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100007868","name":"SECyT","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007868","id-type":"DOI","asserted-by":"crossref"}]},{"name":"UBA 012"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Dentistry"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To associate radiographic and histopathological features of pericoronal follicles (PFs) of asymptomatic impacted teeth and evaluate cell proliferation and apoptosis in the epithelium.<jats:italic>Study Design<\/jats:italic>. Epithelium and mesenchyme of radiographically normal (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mtext>NPF<\/mml:mtext><mml:mo>\u2264<\/mml:mo><mml:mn fontstyle=\"italic\">2.5<\/mml:mn><\/mml:math>\u2009mm) and hyperplastic (HPF 2.6 to 5\u2009mm) PF (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">140<\/mml:mn><\/mml:math>) were studied histologically. Cell proliferation (PI) and epithelial apoptosis were evaluated by Ki-67 and bcl-2 expression in 14 NPFs and 10 dentigerous cysts (DCs).<jats:italic>Results<\/jats:italic>. Radiographically, 127 were NPFs and 13 were HPFs; 87.8% of total PFs exhibited epithelium on the surface. Reduced enamel epithelium was observed in 78 (61.4%) NPFs and 6 (46.2%) HPFs, squamous metaplasia in 17 (13.4%) NPFs and 4 (30.8%) HPFs, and cystic epithelium in 15 (11.8%) NPFs and 3 (23%) HPFs. Mean PI was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn fontstyle=\"italic\">1.97<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">1.25<\/mml:mn><\/mml:math>and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mn fontstyle=\"italic\">7.97<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">1.74<\/mml:mn><\/mml:math>in the epithelial component of NPF and DC, respectively; bcl-2 positive expression was observed in 9 (64.3%) NPFs and 7 (70%) DCs.<jats:italic>Conclusion<\/jats:italic>. The scant epithelial remnant proliferation could imply low risk for development of odontogenic pathologies in the absence of an additional stimulus.<\/jats:p>","DOI":"10.1155\/2012\/935310","type":"journal-article","created":{"date-parts":[[2012,1,23]],"date-time":"2012-01-23T16:18:20Z","timestamp":1327335500000},"page":"1-6","source":"Crossref","is-referenced-by-count":18,"title":["Pericoronal Follicles of Asymptomatic Impacted Teeth: A Radiographic, Histomorphologic, and Immunohistochemical Study"],"prefix":"10.1155","volume":"2012","author":[{"given":"Laura","family":"Villalba","sequence":"first","affiliation":[{"name":"Department of Oral Pathology, School of Dentistry, University of Buenos Aires, 1122 Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Stolbizer","sequence":"additional","affiliation":[{"name":"Department of Buccomaxillofacial Surgery and Traumatology, School of Dentistry, University of Buenos Aires, 1122 Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabi\u00e1n","family":"Blasco","sequence":"additional","affiliation":[{"name":"Department of Buccomaxillofacial Surgery and Traumatology, School of Dentistry, University of Buenos Aires, 1122 Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e9stor Ra\u00fal","family":"Mauri\u00f1o","sequence":"additional","affiliation":[{"name":"Department of Buccomaxillofacial Surgery and Traumatology, School of Dentistry, University of Buenos Aires, 1122 Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Julia","family":"Piloni","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology, School of Dentistry, University of Buenos Aires, 1122 Buenos Aires, 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