{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:26:14Z","timestamp":1740147974986,"version":"3.37.3"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 99-2622-E-155-007-CC2","NSC100-2911-I-008-001"],"award-info":[{"award-number":["NSC 99-2622-E-155-007-CC2","NSC100-2911-I-008-001"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 99-2622-E-155-007-CC2","NSC100-2911-I-008-001"],"award-info":[{"award-number":["NSC 99-2622-E-155-007-CC2","NSC100-2911-I-008-001"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>A detrended fluctuation analysis (DFA) method is applied to image analysis. The 2-dimensional (2D) DFA algorithms is proposed for recharacterizing images of lymph sections. Due to Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), there is a significant different 5-year survival rates after multiagent chemotherapy. Therefore, distinguishing the difference between BL and DLBCL is very important. In this study, eighteen BL images were classified as group A, which have one to five cytogenetic changes. Ten BL images were classified as group B, which have more than five cytogenetic changes. Both groups A and B BLs are aggressive lymphomas, which grow very fast and require more intensive chemotherapy. Finally, ten DLBCL images were classified as group C. The short-term correlation exponent<jats:italic>\u03b1<\/jats:italic>1 values of DFA of groups A, B, and C were<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mn>0.370<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.033<\/mml:mn><\/mml:mrow><\/mml:math>,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mn>0.382<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.022,<\/mml:mn><\/mml:mrow><\/mml:math>and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mn>0.435<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.053<\/mml:mn><\/mml:mrow><\/mml:math>, respectively. It was found that<jats:italic>\u03b1<\/jats:italic>1 value of BL image was significantly lower (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>) than DLBCL. However, there is no difference between the groups A and B BLs. Hence, it can be concluded that<jats:italic>\u03b1<\/jats:italic>1 value based on DFA statistics concept can clearly distinguish BL and DLBCL image.<\/jats:p>","DOI":"10.1155\/2012\/947191","type":"journal-article","created":{"date-parts":[[2012,12,29]],"date-time":"2012-12-29T16:01:33Z","timestamp":1356796893000},"page":"1-8","source":"Crossref","is-referenced-by-count":3,"title":["Two-Dimensional Matrix Algorithm Using Detrended Fluctuation Analysis to Distinguish Burkitt and Diffuse Large B-Cell Lymphoma"],"prefix":"10.1155","volume":"2012","author":[{"given":"Rong-Guan","family":"Yeh","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, Yuan Ze University, 135 Yuan-Tung Road, Chungli 32003, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Wu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Pathology, National Taiwan University Hospital, Taipei 100, 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