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We determined the consistency of positive interferon-gamma (IFN-\u03b3) release assays (IGRAs) to detect latent TB infection (LTBI) over one-year postpartum in HIV-1-infected women.<jats:italic>Methods<\/jats:italic>. Women with positive IGRAs during pregnancy had four 3-monthly postpartum IGRAs. Postpartum change in magnitude of IFN-\u03b3 response was determined using linear mixed models.<jats:italic>Results<\/jats:italic>. Among 18 women with positive pregnancy IGRA, 15 (83%) had a subsequent positive IGRA; 9 (50%) were always positive, 3 (17%) were always negative, and 6 (33%) fluctuated between positive and negative IGRAs. Women with pregnancy IGRA IFN-\u03b3<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mo>&gt;<\/mml:mo><mml:mn>8<\/mml:mn><\/mml:math>spot forming cells (SFCs)\/well were more likely to have consistent postpartum IGRA response (odds ratio: 10.0; 95% confidence interval (CI): 0.9\u2013117.0). Change in IFN-\u03b3 response over postpartum was 10.2 SFCs\/well (95% CI: \u22121.5\u201321.8 SFCs\/well).<jats:italic>Conclusion<\/jats:italic>. Pregnancy positive IGRAs were often maintained postpartum with increased consistency in women with higher baseline responses. There were modest increases in magnitude of IGRA responses postpartum.<\/jats:p>","DOI":"10.1155\/2012\/950650","type":"journal-article","created":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T17:55:55Z","timestamp":1331834155000},"page":"1-7","source":"Crossref","is-referenced-by-count":6,"title":["Consistency of<i>Mycobacterium tuberculosis<\/i>-Specific Interferon-Gamma Responses in HIV-1-Infected Women during Pregnancy and Postpartum"],"prefix":"10.1155","volume":"2012","author":[{"given":"Sasi R.","family":"Jonnalagadda","sequence":"first","affiliation":[{"name":"Department of Epidemiology, University of Washington, 325 9th Avenue, Seattle, WA 98104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Washington, 325 9th Avenue, Seattle, WA 98104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Lohman-Payne","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Washington, 325 9th Avenue, Seattle, WA 98104, USA"},{"name":"Department of Global Health, University of Washington, 325 9th Avenue, Seattle, WA 98104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalton","family":"Wamalwa","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, University of Nairobi, P.O. 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