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The oxygen-induced retinopathy rat model of ROP presents neurovascular outcomes similar to the human disease, although it is not yet known if the \u201cROP rat\u201d also models the small-eyed myopia characteristic of ROP. In this study, magnetic resonance images (MRIs) of albino (Sprague-Dawley) and pigmented (Long-Evans) ROP rat eyes, and age- and strain-matched room-air-reared (RAR) controls, were examined. The positions and curvatures of the various optical media were measured and the refractive state (\u211e) of each eye estimated based on a previously published model. Even in adulthood (postnatal day 50), Sprague-Dawley and Long-Evans ROP rats were significantly myopic compared to strain-matched controls. The myopia in the Long-Evans ROP rats was more severe than in the Sprague-Dawley ROP rats, which also had significantly shorter axial lengths. These data reveal the ROP rat to be a novel and potentially informative approach to investigating physiological mechanisms in myopia in general and the myopia peculiar to ROP in particular.<\/jats:p>","DOI":"10.1155\/2012\/956705","type":"journal-article","created":{"date-parts":[[2012,2,8]],"date-time":"2012-02-08T21:04:19Z","timestamp":1328735059000},"page":"1-15","source":"Crossref","is-referenced-by-count":3,"title":["Refractive Development in the \u201cROP Rat\u201d"],"prefix":"10.1155","volume":"2012","author":[{"given":"Toco Y. 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