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Ophthalmic sequelae have been extensively studied in children and adolescents with Down syndrome but less often in older adults. In-depth review of medical records of older adults with Down syndrome indicated that ophthalmic disorders were common. Cataracts were the most frequent ophthalmic disorder reported, followed by refractive errors, strabismus, and presbyopia. Severity of intellectual disability was unrelated to the presence of ophthalmic disorders. Also, ophthalmic disorders were associated with lower vision-dependent functional and cognitive abilities, although not to the extent that was expected. The high prevalence of ophthalmic disorders highlights the need for periodic evaluations and individualized treatment plans for adults with Down syndrome, in general, but especially when concerns are identified.<\/jats:p>","DOI":"10.1155\/2012\/974253","type":"journal-article","created":{"date-parts":[[2012,4,18]],"date-time":"2012-04-18T21:02:05Z","timestamp":1334782925000},"page":"1-9","source":"Crossref","is-referenced-by-count":35,"title":["Ophthalmic Disorders in Adults with Down Syndrome"],"prefix":"10.1155","volume":"2012","author":[{"given":"Sharon J.","family":"Krinsky-McHale","sequence":"first","affiliation":[{"name":"Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmund C.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren B.","family":"Zigman","sequence":"additional","affiliation":[{"name":"Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Silverman","sequence":"additional","affiliation":[{"name":"Department of Behavioral Psychology, Kennedy Krieger Institute and Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 707 N. 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