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of soft tissues quantitatively. Young\u2019s modulus of soft tissue can be calculated from the force-deformation data with known tissue thickness and Poisson\u2019s ratio using Hayes\u2019 equation. Our group previously developed a noncontact indentation system using a water jet as a soft indenter as well as the coupling medium for the propagation of high-frequency ultrasound. The novel system has shown its ability to detect the early degeneration of articular cartilage. However, there is still lack of a quantitative method to extract the intrinsic mechanical properties of soft tissue from water jet indentation. The purpose of this study is to investigate the relationship between the loading-unloading curves and the mechanical properties of soft tissues to provide an imaging technique of tissue mechanical properties. A 3D finite element model of water jet indentation was developed with consideration of finite deformation effect. An improved Hayes\u2019 equation has been derived by introducing a new scaling factor which is dependent on Poisson\u2019s ratios<jats:italic>v<\/jats:italic>, aspect ratio<jats:italic>a\/h<\/jats:italic>(the radius of the indenter\/the thickness of the test tissue), and deformation ratio<jats:italic>d\/h<\/jats:italic>. With this model, the Young\u2019s modulus of soft tissue can be quantitatively evaluated and imaged with the error no more than 2%.<\/jats:p>","DOI":"10.1155\/2012\/979847","type":"journal-article","created":{"date-parts":[[2012,8,15]],"date-time":"2012-08-15T17:01:12Z","timestamp":1345050072000},"page":"1-6","source":"Crossref","is-referenced-by-count":6,"title":["Quantitative Imaging of Young\u2019s Modulus of Soft Tissues from Ultrasound Water Jet Indentation: A Finite Element Study"],"prefix":"10.1155","volume":"2012","author":[{"given":"Min-Hua","family":"Lu","sequence":"first","affiliation":[{"name":"National-Regional Engineering Laboratory for Key Technology of Medical Ultrasound, Shenzhen University, Shenzhen 518060, China"},{"name":"Guangdong Key Laboratory of Biomedical Information Detection and Ultrasound Imaging, Shenzhen University, Shenzhen 518060, China"},{"name":"Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen 518060, 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