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In children, RRF was shown not only to help preserve adequacy of renal replacement therapy but also to accelerate growth rate, improve nutrition and blood pressure control, reduce the risk of adverse myocardial changes, facilitate treatment of anemia and calcium\u2010phosphorus balance abnormalities, and result in reduced serum and dialysate fluid levels of advanced glycation end\u2010products. Factors contributing to RRF loss in children treated with peritoneal dialysis include the underlying renal disease such as hemolytic\u2010uremic syndrome and hereditary nephropathy, small urine volume, severe proteinuria at the initiation of renal replacement therapy, and hypertension. Several approaches can be suggested to decrease the rate of RRF loss in pediatric patients treated with chronic peritoneal dialysis: potentially nephrotoxic drugs (e.g., aminoglycosides), episodes of hypotension, and uncontrolled hypertension should be avoided, urinary tract infections should be treated promptly, and loop diuretics may be used to increase salt and water excretion.<\/jats:p>","DOI":"10.1155\/2013\/154537","type":"journal-article","created":{"date-parts":[[2013,11,24]],"date-time":"2013-11-24T21:00:53Z","timestamp":1385326853000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Residual Renal Function in Children Treated with Chronic Peritoneal Dialysis"],"prefix":"10.1155","volume":"2013","author":[{"given":"Maria","family":"Roszkowska-Blaim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1959-8255","authenticated-orcid":false,"given":"Piotr","family":"Skrzypczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,24]]},"reference":[{"key":"e_1_2_8_1_2","first-page":"1","article-title":"NKF KDOQI 2006 updates clinical practice guidelines and clinical practice recommendations for hemodialysis adequacy, peritoneal dialysis adequacy and vascular access","volume":"48","year":"2006","journal-title":"The American Journal of Kidney Diseases"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0894-0959.2004.17306.x"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00858132"},{"key":"e_1_2_8_4_2","first-page":"269","article-title":"Effects of automated peritoneal dialysis on residual daily urinary volume in children","volume":"17","author":"Fischbach M.","year":"2001","journal-title":"Advances in Peritoneal Dialysis"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.58.2.259"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.51.11.875"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-6-199903160-00002"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000180580"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-010-1678-8"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1996.32"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365513.2011.619565"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-78940-8_16"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-78940-8_29"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(97)70028-3"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(01)70006-6"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00169.x"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/089686080502500212"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V1351307"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00098.x"},{"key":"e_1_2_8_20_2","first-page":"83","article-title":"Discrepancy between weekly KT\/V and weekly creatinine clearance in patients on CAPD","volume":"11","author":"Chen H. 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