{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T07:50:49Z","timestamp":1778226649944,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31070828"],"award-info":[{"award-number":["31070828"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31271005"],"award-info":[{"award-number":["31271005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["11032008"],"award-info":[{"award-number":["11032008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2012T50247"],"award-info":[{"award-number":["2012T50247"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["20100471587"],"award-info":[{"award-number":["20100471587"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2009021018-2"],"award-info":[{"award-number":["2009021018-2"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31070828"],"award-info":[{"award-number":["31070828"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31271005"],"award-info":[{"award-number":["31271005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["11032008"],"award-info":[{"award-number":["11032008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2012T50247"],"award-info":[{"award-number":["2012T50247"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["20100471587"],"award-info":[{"award-number":["20100471587"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2009021018-2"],"award-info":[{"award-number":["2009021018-2"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31070828"],"award-info":[{"award-number":["31070828"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31271005"],"award-info":[{"award-number":["31271005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["11032008"],"award-info":[{"award-number":["11032008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2012T50247"],"award-info":[{"award-number":["2012T50247"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["20100471587"],"award-info":[{"award-number":["20100471587"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2009021018-2"],"award-info":[{"award-number":["2009021018-2"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["31070828"],"award-info":[{"award-number":["31070828"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["31271005"],"award-info":[{"award-number":["31271005"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["11032008"],"award-info":[{"award-number":["11032008"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2012T50247"],"award-info":[{"award-number":["2012T50247"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["20100471587"],"award-info":[{"award-number":["20100471587"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2009021018-2"],"award-info":[{"award-number":["2009021018-2"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["31070828"],"award-info":[{"award-number":["31070828"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["31271005"],"award-info":[{"award-number":["31271005"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["11032008"],"award-info":[{"award-number":["11032008"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2012T50247"],"award-info":[{"award-number":["2012T50247"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["20100471587"],"award-info":[{"award-number":["20100471587"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2009021018-2"],"award-info":[{"award-number":["2009021018-2"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Natural Science Foundation of Shanxi","award":["31070828"],"award-info":[{"award-number":["31070828"]}]},{"name":"Natural Science Foundation of Shanxi","award":["31271005"],"award-info":[{"award-number":["31271005"]}]},{"name":"Natural Science Foundation of Shanxi","award":["11032008"],"award-info":[{"award-number":["11032008"]}]},{"name":"Natural Science Foundation of Shanxi","award":["2012T50247"],"award-info":[{"award-number":["2012T50247"]}]},{"name":"Natural Science Foundation of Shanxi","award":["20100471587"],"award-info":[{"award-number":["20100471587"]}]},{"name":"Natural Science Foundation of Shanxi","award":["2009021018-2"],"award-info":[{"award-number":["2009021018-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>For a more detailed description of the interaction between residues, this paper proposes an amino acid network model, which contains two types of weight\u2014similar weight and dissimilar weight. The weight of the link is based on a self-consistent statistical contact potential between different types of amino acids. In this model, we can get a more reasonable representation of the distance between residues. Furthermore, with the network parameter, average shortest path length, we can get a more accurate reflection of the molecular size. This amino acid network is a \u201csmall-world\u201d network, and the network parameter is sensitive to the conformation change of protein. For some disease-related proteins, the highly central residues of the amino acid network are highly correlated with the hot spots. In the compound with the related drug, these residues either interacted directly with the drug or with the residue which is in contact with the drug.<\/jats:p>","DOI":"10.1155\/2013\/197892","type":"journal-article","created":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T14:14:19Z","timestamp":1369750459000},"page":"1-8","source":"Crossref","is-referenced-by-count":3,"title":["A Modified Amino Acid Network Model Contains Similar and Dissimilar Weight"],"prefix":"10.1155","volume":"2013","author":[{"given":"Xiong","family":"Jiao","sequence":"first","affiliation":[{"name":"Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifeng","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Computer Science and Technology (College of Software), Taiyuan University of Technology, Taiyuan 030024, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiwen","family":"An","sequence":"additional","affiliation":[{"name":"Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiyi","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1103\/RevModPhys.74.47"},{"issue":"2","key":"2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1137\/S003614450342480","volume":"45","year":"2003","journal-title":"SIAM Review"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.65.061910"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.122076099"},{"issue":"6","key":"5","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/bfgp\/els023","volume":"11","year":"2012","journal-title":"Briefings in Functional Genomics"},{"key":"6"},{"issue":"1 i","key":"7","first-page":"85","volume":"86","year":"2004","journal-title":"Biophysical Journal"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.105.064485"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2003.08.061"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019238"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1996.0114"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0134(19990101)34:1<49::AID-PROT5>3.0.CO;2-L"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1080\/00018730601170527"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.75.051903"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.physa.2006.03.056"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0400087101"},{"issue":"1","key":"18","volume":"67","year":"2003","journal-title":"Physical Review E"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1002\/prot.20348"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/S008940100045"},{"issue":"6684","key":"21","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/30918","volume":"393","year":"1998","journal-title":"Nature"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhj127"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg1069"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-7799(02)02053-X"},{"key":"25","year":"2004"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzl009"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2009.11.017"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1002\/bip.21494"},{"issue":"10, article e25560","key":"29","volume":"6","year":"2011","journal-title":"PloS One"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.2174\/138161212802651599"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-378"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.3390\/ijms12128773"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2007.12.005"},{"issue":"5007","key":"34","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1126\/science.1709302","volume":"252","year":"1991","journal-title":"Science"},{"issue":"5172","key":"35","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1126\/science.7518616","volume":"265","year":"1994","journal-title":"Science"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90124-H"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444999016571"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1021\/ja00019a057"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2013\/197892.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2013\/197892.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2013\/197892.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T09:45:06Z","timestamp":1498038306000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cmmm\/2013\/197892\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":37,"alternative-id":["197892","197892"],"URL":"https:\/\/doi.org\/10.1155\/2013\/197892","relation":{},"ISSN":["1748-670X","1748-6718"],"issn-type":[{"value":"1748-670X","type":"print"},{"value":"1748-6718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}