{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:47:29Z","timestamp":1790628449234,"version":"4.1.0"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal testing were done with lidocaine, mepivacaine, and procaine. Intradermal testing showed positive reactions to mepivacaine (1\u2009:\u200910), undiluted lidocaine, and procaine (1\u2009:\u200910 and undiluted). Specific IgE could be detected against mepivacaine, but not against latex. Serum tryptase was in the normal range. In order to rule out the exceptional case of a true IgE-mediated reaction, allergy testing with local anaesthetics is still required in the workup of patients.<\/jats:p>","DOI":"10.1155\/2013\/201586","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T17:15:40Z","timestamp":1369934140000},"page":"1-3","source":"Crossref","is-referenced-by-count":11,"title":["The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5417-1874","authenticated-orcid":true,"given":"Christina","family":"Fellinger","sequence":"first","affiliation":[{"name":"Floridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8\/6, 1210 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Wantke","sequence":"additional","affiliation":[{"name":"Floridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8\/6, 1210 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Hemmer","sequence":"additional","affiliation":[{"name":"Floridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8\/6, 1210 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Sesztak-Greinecker","sequence":"additional","affiliation":[{"name":"Floridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8\/6, 1210 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6324-0007","authenticated-orcid":true,"given":"Stefan","family":"W\u00f6hrl","sequence":"additional","affiliation":[{"name":"Floridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8\/6, 1210 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1159\/000315952"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2008.01366.x"},{"issue":"2","key":"3","first-page":"91","volume":"15","year":"2005","journal-title":"Journal of Investigational Allergology and Clinical Immunology"},{"key":"4","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1093\/bja\/aes162","volume":"108","year":"2012","journal-title":"British Journal of Anaesthesia"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2009.02193.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(96)80067-4"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2006.01148.x"},{"key":"8","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1600-0536.2012.02149.x","volume":"68","year":"2013","journal-title":"Contact Dermatitis"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2013\/201586.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2013\/201586.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2013\/201586.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T09:53:42Z","timestamp":1498038822000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2013\/201586\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":8,"alternative-id":["201586","201586"],"URL":"https:\/\/doi.org\/10.1155\/2013\/201586","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}