{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:26:40Z","timestamp":1770269200277,"version":"3.49.0"},"reference-count":33,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anemia"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Identification and management of risk factors for stroke following isolated coronary artery bypass grafting (CABG) could potentially lower the risk of such serious morbidity.<jats:italic>Methods<\/jats:italic>. We retrieved data for 30-day stroke incidence and perioperative variables for patients undergoing isolated CABG and used multivariate logistic regression to assess the adjusted effect of preoperative hematocrit concentration on stroke incidence.<jats:italic>Results<\/jats:italic>. In 2,313 patients (mean age 65.9 years, 73.6% men), 43 (1.9%, 95% CI: 1.4\u20132.5) developed stroke within 30 days following CABG (74.4% within 6 days). After adjustment for a priori defined potential confounders, each 1% drop in preoperative hematocrit concentration was associated with 1.07 (95% CI: 1.01\u20131.13) increased odds for stroke (men, OR: 1.08, 95% CI: 1.01\u20131.16; women, OR: 1.02, 95% CI: 0.91\u20131.16). The predicted probability of stroke for descending preoperative hematocrit concentration exceeded 2% for values &lt;37% (&lt;37% for men (adjusted OR: 2.39, 95% CI: 1.08\u20135.26) and &lt;38% for women (adjusted OR: 2.52, 95% CI: 0.53\u201311.98), with a steeper probability increase noted in men). The association between lower preoperative hematocrit concentration and stroke was evident irrespective of intraoperative transfusion use.<jats:italic>Conclusion<\/jats:italic>. Screening and management of patients with low preoperative hematocrit concentration may alter postoperative stroke risk in patients undergoing isolated CABG.<\/jats:p>","DOI":"10.1155\/2013\/206829","type":"journal-article","created":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T21:40:23Z","timestamp":1367444423000},"page":"1-7","source":"Crossref","is-referenced-by-count":8,"title":["Preoperative Hematocrit Concentration and the Risk of Stroke in Patients Undergoing Isolated Coronary-Artery Bypass Grafting"],"prefix":"10.1155","volume":"2013","author":[{"given":"Khaled M.","family":"Musallam","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut 1107 2020, Lebanon"},{"name":"Angelo Bianchi Bonomi Haemophilia and Thrombosis Center, Department of Medicine and Medical Specialties, IRCCS Ca\u2019 Granda Foundation Maggiore Policlinico Hospital, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faek R.","family":"Jamali","sequence":"additional","affiliation":[{"name":"Division of General Surgery, Department of Surgery, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut 1107 2020, Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frits R.","family":"Rosendaal","sequence":"additional","affiliation":[{"name":"Departments of Clinical Epidemiology and Thrombosis & Hemostasis, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toby","family":"Richards","sequence":"additional","affiliation":[{"name":"Division of Surgery and Interventional Science, University College London Hospital, London WC1E 6AU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donat R.","family":"Spahn","sequence":"additional","affiliation":[{"name":"Institute of Anesthesiology, University Hospital and University of Zurich, 8006 Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaivan","family":"Khavandi","sequence":"additional","affiliation":[{"name":"King\u2019s College London British Heart Foundation Centre, The Rayne Institute, St. Thomas\u2019 Hospital, King\u2019s Health Partners AHSC, London SE1 7EH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iskandar","family":"Barakat","sequence":"additional","affiliation":[{"name":"Department of Medicine, Staten Island University Hospital, New York, NY 10305, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Demoss","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca A.","family":"Lotta","sequence":"additional","affiliation":[{"name":"Angelo Bianchi Bonomi Haemophilia and Thrombosis Center, Department of Medicine and Medical Specialties, IRCCS Ca\u2019 Granda Foundation Maggiore Policlinico Hospital, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flora","family":"Peyvandi","sequence":"additional","affiliation":[{"name":"Angelo Bianchi Bonomi Haemophilia and Thrombosis Center, Department of Medicine and Medical Specialties, IRCCS Ca\u2019 Granda Foundation Maggiore Policlinico Hospital, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pier M.","family":"Sfeir","sequence":"additional","affiliation":[{"name":"Division of General Surgery, Department of Surgery, American University of Beirut Medical Center, P.O. 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