{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T20:12:22Z","timestamp":1787861542698,"version":"build-2784847793"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>A 70-year-old man was admitted to our hospital because of weight loss and persistent dry cough. Chest radiograph and CT showed multiple infiltrates in the bilateral upper lobes and the remarkably thickened bronchial walls. Bronchoscopy revealed diffuse erythema and edema of the tracheobronchial mucosa without any ulcerous legions. Serum MPO-ANCA was positive (155 EU). Transbronchial biopsy was performed and revealed necrotic granulomas with multinucleated giant cells in the bronchial\/bronchiolar and parenchymal lesions. Thus, we diagnosed it as a localized form of granulomatosis with polyangiitis (GPA, Wegener\u2019s granulomatosis). After treatment with corticosteroid and cyclophosphamide, the bronchial findings were entirely resolved. We report here a rare case of GPA presenting with markedly inflamed tracheobronchial mucosa.<\/jats:p>","DOI":"10.1155\/2013\/208194","type":"journal-article","created":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T03:15:11Z","timestamp":1380597311000},"page":"1-5","source":"Crossref","is-referenced-by-count":5,"title":["A Case of Granulomatosis with Polyangiitis (Wegener\u2019s Granulomatosis) Presenting with Marked Inflamed Tracheobronchial Mucosa"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9390-8031","authenticated-orcid":true,"given":"Teruaki","family":"Nishiuma","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Akashi Medical Center, 743-33 Yagi, Okubo-cho, Akashi, Hyogo 674-0063, Japan"},{"name":"Department of Respiratory Medicine, Kakogawa West City Hospital, 384-1 Hiratsu, Yoneda-cho, Kakogawa, Hyogo 675-8611, 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