{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:31:19Z","timestamp":1788406279595,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>\n                    In the Indian traditional system of medicine\n                    <jats:italic>Operculina turpethum<\/jats:italic>\n                    is commonly used to treat various ailments including peptic ulcer, inflammation, and pain. Ulcer preventive and ulcer protective activities of HAOP and MOP stem bark extracts of\n                    <jats:italic>Operculina turpethum<\/jats:italic>\n                    (100\u2009mg\/kg, b.w., orally) were evaluated employing aspirin + pylorus ligation (APL) model in experimental rats. The results suggested that both extracts (HAOP and MOP) possess enhanced ulcer preventive and protective activities when compared with the standard drug ranitidine. HAOP showed more pronounced effect when compared to MOP. Further the result of the histopathological and biochemical studies also confirms potent ulcer preventive and protective nature of a extracts in a similar manner.\n                  <\/jats:p>","DOI":"10.1155\/2013\/272134","type":"journal-article","created":{"date-parts":[[2013,2,11]],"date-time":"2013-02-11T16:10:10Z","timestamp":1360599010000},"page":"1-7","source":"Crossref","is-referenced-by-count":11,"title":["Antiulcer Activity of Indigenous Plant\n                    <i>Operculina turpethum<\/i>\n                    Linn."],"prefix":"10.1155","volume":"2013","author":[{"given":"Vidya","family":"Ignatius","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Sathyabama University Dental College and Hospital, Sathyabama University, Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, Tamilnadu 600 119, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhusudhanan","family":"Narayanan","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Sathyabama University Dental College and Hospital, Sathyabama University, Jeppiaar Nagar, Rajiv Gandhi Road, Chennai, Tamilnadu 600 119, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkataraman","family":"Subramanian","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Environmental Toxicology, Dr. ALM Post Graduate Institute of Basic Medical Science, University of Madras, Taramani Campus, Chennai, Tamilnadu 600 113, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balasubramanian Maruthaiveeran","family":"Periyasamy","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Environmental Toxicology, Dr. ALM Post Graduate Institute of Basic Medical Science, University of Madras, Taramani Campus, Chennai, Tamilnadu 600 113, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2006.10.017"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.09.007"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.05.014"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.02.035"},{"key":"5","volume":"8","year":"2000"},{"issue":"6","key":"6","first-page":"265","volume":"3","year":"1982","journal-title":"Economic Botany"},{"key":"7","year":"1982"},{"key":"8","volume":"4","year":"1995"},{"issue":"2","key":"9","doi-asserted-by":"crossref","first-page":"228","DOI":"10.4103\/0974-8520.72405","volume":"31","year":"2010","journal-title":"Ayu"},{"issue":"3","key":"10","first-page":"171","volume":"13","year":"1987","journal-title":"Acta Cienc Indica Chemistry"},{"key":"11","volume":"2","year":"1979"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2004.12.024"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2007.04.007"},{"issue":"2","key":"14","first-page":"40","volume":"3","year":"2010","journal-title":"Plant OMICS"},{"issue":"9","key":"15","doi-asserted-by":"crossref","first-page":"272","DOI":"10.3329\/icpj.v1i9.11618","volume":"1","year":"2012","journal-title":"International Current Pharmaceutical Journal"},{"key":"16","first-page":"224","volume":"19","year":"1982","journal-title":"Indian Drugs"},{"issue":"1","key":"17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.4103\/0250-474X.22960","volume":"68","year":"2006","journal-title":"Indian Journal of Pharmaceutical Sciences"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2009.06.021"},{"issue":"1","key":"19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0378-8741(86)90041-3","volume":"18","year":"1986","journal-title":"Journal of Ethnopharmacology"},{"key":"20","first-page":"43","volume":"5","year":"1945","journal-title":"Gastroenterology"},{"issue":"6","key":"21","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0016-5085(54)80008-4","volume":"26","year":"1954","journal-title":"Gastroenterology"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/0160-5402(85)90068-3"},{"issue":"13","key":"23","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/0024-3205(87)90734-X","volume":"41","year":"1987","journal-title":"Life Sciences"},{"key":"24","volume-title":"Peptic ulcer and gastritis","year":"1991"},{"issue":"8","key":"25","first-page":"701","volume":"29","year":"1991","journal-title":"Indian Journal of Experimental Biology"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/541624"},{"key":"27","series-title":"Edited by B. L. Oster","year":"1965"},{"issue":"1","key":"28","first-page":"71","volume":"36","year":"2007","journal-title":"Journal of Zhejiang University"},{"issue":"2","key":"29","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0304-4165(72)90230-9","volume":"273","year":"1972","journal-title":"Biochimica et Biophysica Acta"},{"issue":"2","key":"30","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jams.2012.01.004","volume":"5","year":"2012","journal-title":"Journal of Acupuncture Meridian Studies"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2006.12.025"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.4103\/0250-474X.70486"},{"issue":"4","key":"33","first-page":"886","volume":"1","year":"2010","journal-title":"Research Journal of Pharmaceutical, Biological and Chemical Sciences"},{"issue":"3","key":"34","first-page":"243","volume":"5","year":"2012","journal-title":"Al Ameen Journal of Medical Science"},{"issue":"2","key":"35","first-page":"78","volume":"21","year":"1983","journal-title":"Indian Journal of Experimental Biology"},{"issue":"4","key":"36","first-page":"337","volume":"28","year":"1990","journal-title":"Indian Journal of Experimental Biology"},{"issue":"5","key":"37","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1590\/S0100-879X2002000500003","volume":"35","year":"2002","journal-title":"Brazilian Journal of Medical and Biological Research"},{"issue":"12","key":"38","first-page":"168","volume":"2","year":"2012","journal-title":"BMC Complementary and Alternative Medicine"},{"issue":"1-2","key":"39","first-page":"21","volume":"18","year":"2003","journal-title":"Nigerian Journal of Physiological Sciences"},{"issue":"1-2","key":"40","first-page":"79","volume":"23","year":"2008","journal-title":"Nigerian Journal of Physiological Sciences"},{"issue":"4","key":"41","first-page":"15","volume":"5","year":"2010","journal-title":"Science World Journal"},{"issue":"4","key":"42","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s12253-012-9541-9","volume":"18","year":"2012","journal-title":"Pathology and Oncology Research"},{"issue":"5","key":"43","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1016\/j.fct.2012.02.042","volume":"50","year":"2012","journal-title":"Food and Chemical Toxicology"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1006\/phrs.1999.0601"},{"issue":"1","key":"45","doi-asserted-by":"crossref","first-page":"48","DOI":"10.4103\/0250-474X.102543","volume":"74","year":"2012","journal-title":"Indian Journal of Pharmaceutical Sciences"},{"issue":"9","key":"46","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.3736\/jcim20110915","volume":"9","year":"2011","journal-title":"Zhong Xi Yi Jie He Xue Bao"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/272134.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/272134.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/272134.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T12:04:40Z","timestamp":1562673880000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ecam\/2013\/272134\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":46,"alternative-id":["272134","272134"],"URL":"https:\/\/doi.org\/10.1155\/2013\/272134","relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}