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A chloroform extract obtained from octopus tentacles was sequentially fractionated using thin layer chromatography (TLC), and each fraction was tested for antimutagenic and antiproliferative activities. Organic extract reduced the number of revertants caused by aflatoxin B<jats:sub>1<\/jats:sub>showing a dose-response type of relationship. Sequential TLC fractionation of the active extracts produced several antimutagenic and\/or antiproliferative fractions. Based on the results obtained, the isolated fractions obtained from octopus contain compounds with chemoprotective properties that reduce the mutagenicity of AFB<jats:sub>1<\/jats:sub>and proliferation of cancer cell lines.<\/jats:p>","DOI":"10.1155\/2013\/273582","type":"journal-article","created":{"date-parts":[[2013,1,16]],"date-time":"2013-01-16T16:02:52Z","timestamp":1358352172000},"page":"1-12","source":"Crossref","is-referenced-by-count":5,"title":["Bioactive Lipidic Extracts from Octopus (<i>Paraoctopus limaculatus<\/i>): Antimutagenicity and Antiproliferative Studies"],"prefix":"10.1155","volume":"2013","author":[{"given":"Carolina","family":"Moreno-F\u00e9lix","sequence":"first","affiliation":[{"name":"Departamento de Investigaci\u00f3n y Posgrado en Alimentos, Universidad de Sonora, Apartado Postal 1658, 83000 Hermosillo, SON, 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