{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:30:57Z","timestamp":1772109057634,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. This study assessed the posttreatment tumor control and auditory function of vestibular schwannoma (VS) patients after CyberKnife (CK) and analyzed the possible prognostic factors of hearing loss.<jats:italic>Methods<\/jats:italic>. We retrospectively studied 117 VS patients, with Gardner-Robertson (GR) classification grades I to IV, who underwent CK between 2006 and 2012. Data including radiosurgery treatment parameters, pre- and postoperative tumor size, and auditory function were collected and examined.<jats:italic>Results<\/jats:italic>. With CK, 117 patients had excellent tumor control rates (99.1%), with a mean imaging followup of 61.1 months. Excluding 52 patients (GR III-IV pretreatment), 53 (81.5%) of the remaining 65 patients (initial GR I-II) maintained GR I or II hearing after CK, with a mean audiometric followup of 64.5 months. Twelve patients experienced hearing degradation (91.6% were GR II pretreatment); they appeared to have significantly larger tumor sizes, significantly smaller cochlear sizes, and higher prescribed cochlear doses, compared to the patients with preserved hearing.<jats:italic>Conclusion<\/jats:italic>. Our data showed that CK treatment provided an excellent tumor control rate and a comparable hearing preservation rate in VS patients. Patients with pretreatment GR II hearing levels, larger tumor volumes, smaller cochlear sizes, and higher prescribed cochlear doses may have poor hearing prognoses.<\/jats:p>","DOI":"10.1155\/2013\/297093","type":"journal-article","created":{"date-parts":[[2013,11,10]],"date-time":"2013-11-10T13:29:55Z","timestamp":1384090195000},"page":"1-6","source":"Crossref","is-referenced-by-count":36,"title":["Clinical Evaluation of CyberKnife in the Treatment of Vestibular Schwannomas"],"prefix":"10.1155","volume":"2013","author":[{"given":"Jo-Ting","family":"Tsai","sequence":"first","affiliation":[{"name":"Department of Radiation-Oncology, Taipei Medical University Wan-Fang Hospital, Taipei 110, Taiwan"},{"name":"Department of Radiation-Oncology, Taipei Medical University Shuang-Ho Hospital, New Taipei City 23561, 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