{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:20:24Z","timestamp":1782890424869,"version":"3.54.5"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T00:00:00Z","timestamp":1385337600000},"content-version":"vor","delay-in-days":328,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004918","name":"University of Ibadan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004918","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Hypertension"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>\n                    Metabolic syndrome (MS) amplifies hypertension (HTN) associated with increased risk of cardiovascular disease (CVD). MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18\u2013105 years were participants of a cohort study. The International Diabetes Federation (2005) and the National High Blood Pressure Education Program Coordinating Committee criteria were used for MS and HTN classifications, respectively. Anthropometric indices were obtained by standard methods. Levels of fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), and high\u2010density lipoprotein cholesterol (HDLC) were determined by enzymatic methods, while low\u2010density lipoprotein cholesterol (LDLC) was calculated. Data analysed statistically were significant at\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05. 143 (26.8%), 197 (36.9%), and 194 (36.3%) of the traders had normotension, pre\u2010HTN and HTN (stages 1 and 2), respectively. All indices tested except HDLC were significantly different among BP groups (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). Waist to hip (WHR) and waist to height (WHT) ratios were significantly different between HTN groups (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). HTN was associated with MS and female gender (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.05). Metabolic alterations and significant HTN were observed. Treatment of the individual components of the syndrome and improvement of modifiable metabolic factors may be necessary to reduce MS and high BP.\n                  <\/jats:p>","DOI":"10.1155\/2013\/351357","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T18:58:42Z","timestamp":1385405922000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population"],"prefix":"10.1155","volume":"2013","author":[{"given":"M. A.","family":"Charles-Davies","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. A.","family":"Fasanmade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. A.","family":"Olaniyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. E.","family":"Oyewole","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. O.","family":"Owolabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. R.","family":"Adebusuyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. T.","family":"Ajobo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. O.","family":"Ebesunun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Adigun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. S.","family":"Akinlade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U. A.","family":"Fabian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. O.","family":"Popoola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. K.","family":"Rahamon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Okunbolade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Ogunlakin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. G.","family":"Arinola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. O","family":"Agbedana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,25]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/869675"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000107251.49515.c2"},{"key":"e_1_2_6_3_2","first-page":"119","article-title":"Kidney diseases in Africa: aetiological considerations, perculiarities and burden","volume":"41","author":"Okunola O.","year":"2012","journal-title":"African Journal of Medicine and Medical Sciences"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht151"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2009.02.026"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-10-71"},{"key":"e_1_2_6_7_2","first-page":"91","article-title":"Indices of metabolic syndrome in 534 apparently healthy traders in a local market in Ibadan, Nigeria","volume":"9","author":"Charles-Davies M. A.","year":"2012","journal-title":"Journal of US-China Medical Science"},{"key":"e_1_2_6_8_2","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/j.jacc.2003.12.049","article-title":"Prognostic value of the metabolic syndrome in essential hypertension","volume":"43","author":"Schillaci C.","year":"2012","journal-title":"American College of Cardiology"},{"key":"e_1_2_6_9_2","article-title":"The IDF consensus worldwide definition of the metabolic syndrome","author":"International Diabetes Federation","year":"2005","journal-title":"Medscape Diabetes & Endocrinology"},{"key":"e_1_2_6_10_2","first-page":"402","article-title":"Serum testosterone and lipids in relation to sexual dysfunction in males with metabolic syndrome and type2 diabetes mellitus","volume":"2","author":"Umoh U.","year":"2010","journal-title":"International Journal of Medicine and Medical Sciences"},{"key":"e_1_2_6_11_2","first-page":"83","article-title":"Hypertension and the metabolic syndrome","volume":"37","author":"Duvnjak L.","year":"2008","journal-title":"Diabetologia Croatica"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2005.01493.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-2236"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.107.151621"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1613"},{"key":"e_1_2_6_16_2","first-page":"493","article-title":"Leptin concentrations in African blacks with metabolic syndrome and type diabetes mellitus","volume":"8","author":"Fabian U. A.","year":"2011","journal-title":"Journal of the US-China Medical Science"},{"key":"e_1_2_6_17_2","first-page":"421","article-title":"Anthropometric and metabolic indicators in hypertensive patients","volume":"19","author":"Syed S.","year":"2009","journal-title":"Journal of the College of Physicians and Surgeons Pakistan"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802259"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328302ca38"}],"container-title":["International Journal of Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2013\/351357","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/2013\/351357","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2013\/351357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:41:44Z","timestamp":1782848504000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2013\/351357"}},"subtitle":[],"editor":[{"given":"Mandy","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1155\/2013\/351357"],"URL":"https:\/\/doi.org\/10.1155\/2013\/351357","archive":["Portico"],"relation":{},"ISSN":["2090-0384","2090-0392"],"issn-type":[{"value":"2090-0384","type":"print"},{"value":"2090-0392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"2013-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-11-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"351357"}}