{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:16Z","timestamp":1740164596243,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Pure androgen-secreting adrenal adenoma is very rare, and its diagnosis remains a clinical challenge. Its association with resistant hypertension is uncommon and not well understood. We present an 18-year-old female with a 10-year history of hirsutism that was accidentally diagnosed with an adrenal mass during the evaluation of a hypertensive crisis. She had a long-standing history of hirsutism, clitorimegaly, deepening of the voice, and primary amenorrhea. She was phenotypically and socially a male. FSH, LH, prolactin, estradiol, 17-hydroxyprogesterone, and progesterone were normal. Total testosterone and DHEA-S were elevated. Cushing syndrome, primary aldosteronism, pheochromocytoma, and nonclassic congenital adrenal hyperplasia were ruled out. She underwent adrenalectomy and pathology reported an adenoma. At 2-month followup, hirsutism and virilizing symptoms clearly improved and blood pressure normalized without antihypertensive medications, current literature of this unusual illness and it association with hypertension is presented and discussed.<\/jats:p>","DOI":"10.1155\/2013\/356086","type":"journal-article","created":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T17:01:11Z","timestamp":1369846871000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Pure Androgen-Secreting Adrenal Adenoma Associated with Resistant Hypertension"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9450-2073","authenticated-orcid":true,"given":"Ren\u00e9","family":"Rodr\u00edguez-Guti\u00e9rrez","sequence":"first","affiliation":[{"name":"Endocrinology Division, University Hospital \u201cDr. Jos\u00e9 E. Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Le\u00f3n, 64460 Monterrey, NL, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Arturo","family":"Bautista-Medina","sequence":"additional","affiliation":[{"name":"Endocrinology Division, University Hospital \u201cDr. Jos\u00e9 E. Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Le\u00f3n, 64460 Monterrey, NL, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Eugenia","family":"Teniente-Sanchez","sequence":"additional","affiliation":[{"name":"Endocrinology Division, University Hospital \u201cDr. Jos\u00e9 E. Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Le\u00f3n, 64460 Monterrey, NL, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Azucena","family":"Zapata-Rivera","sequence":"additional","affiliation":[{"name":"Endocrinology Division, University Hospital \u201cDr. Jos\u00e9 E. Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Le\u00f3n, 64460 Monterrey, NL, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Montes-Villarreal","sequence":"additional","affiliation":[{"name":"Endocrinology Division, University Hospital \u201cDr. Jos\u00e9 E. Gonz\u00e1lez,\u201d Universidad Autonoma de Nuevo Le\u00f3n, 64460 Monterrey, NL, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp065470"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1490273"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199410133311502"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.189141"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(03)00410-0"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1210\/jc.82.7.2027"},{"issue":"4","key":"8","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/0002-9343(66)90219-1","volume":"41","year":"1966","journal-title":"The American Journal of Medicine"},{"issue":"6","key":"9","first-page":"S57","volume":"8","year":"1990","journal-title":"Journal of Hypertension"},{"key":"10","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/0895-7061(95)00216-2","volume":"8","year":"1995","journal-title":"American Journal of Hypertension"},{"issue":"4","key":"11","first-page":"S3","volume":"77","year":"2002","journal-title":"Fertility and Sterility"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2004.06.046"},{"key":"13","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1002\/(SICI)1097-0142(20000215)88:4<711::AID-CNCR1>3.0.CO;2-W","volume":"88","year":"2000","journal-title":"Cancer"},{"issue":"1","key":"14","first-page":"63","volume":"20","year":"1995","journal-title":"Minerva Endocrinologica"},{"issue":"3","key":"16","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/jso.2930550306","volume":"55","year":"1994","journal-title":"Journal of Surgical Oncology"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025947"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.936674"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr300"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2011.35"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2011.03.001"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2013\/356086.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2013\/356086.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2013\/356086.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T09:49:58Z","timestamp":1498038598000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crie\/2013\/356086\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":20,"alternative-id":["356086","356086"],"URL":"https:\/\/doi.org\/10.1155\/2013\/356086","relation":{},"ISSN":["2090-6501","2090-651X"],"issn-type":[{"type":"print","value":"2090-6501"},{"type":"electronic","value":"2090-651X"}],"subject":[],"published":{"date-parts":[[2013]]}}}