{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T18:18:37Z","timestamp":1790965117150,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Multiple Sclerosis International"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Brain lesions are common in neuromyelitis optica spectrum disorder (NMOsd) and may resemble lesions of multiple sclerosis (MS).\n                    <jats:italic>Objectives<\/jats:italic>\n                    . To describe the imaging characteristics of supratentorial lesions in NMOsd on ultrahigh-field (7\u2009T) MRI with special attention to vessel-lesion relationship.\n                    <jats:italic>Methods<\/jats:italic>\n                    . Ten NMOsd patients, all women and all seropositive for NMO IgG, with mean age of 51.3 \u00b1 15.4 years and disease duration of 9.2 \u00b1 6.4 years, were scanned at a 7\u2009T whole-body human MR system with high-resolution 2D gradient echo sequence optimized to best visualize lesions and venous structures, T2- and T1-weighted imaging.\n                    <jats:italic>Results<\/jats:italic>\n                    . In 10 patients with NMOsd, a total of 92 lesions were observed (mean: 9.2 \u00b1 8.8; range: 2\u201330), but only 8 lesions (9%) were traversed by a central venule. All lesions were &lt;5\u2009mm in diameter, and 83% were located in subcortical white matter. There were no lesions in the cortex or basal ganglia. Two patients exhibited diffuse periependymal abnormalities on FLAIR.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . Small, subcortical lesions without a central venule are the most consistent finding of NMOsd on 7\u2009T MRI of the brain. Ultrahigh-field imaging may be useful for differentiating between NMOsd and MS.\n                  <\/jats:p>","DOI":"10.1155\/2013\/398259","type":"journal-article","created":{"date-parts":[[2013,1,27]],"date-time":"2013-01-27T16:01:10Z","timestamp":1359302470000},"page":"1-7","source":"Crossref","is-referenced-by-count":23,"title":["Ultrahigh-Field MR (7\u2009T) Imaging of Brain Lesions in Neuromyelitis Optica"],"prefix":"10.1155","volume":"2013","author":[{"given":"Ilya","family":"Kister","sequence":"first","affiliation":[{"name":"Multiple Sclerosis Care Center, Department of Neurology, NYU School of Medicine, New York, NY 10016, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Herbert","sequence":"additional","affiliation":[{"name":"Multiple Sclerosis Care Center, Department of Neurology, NYU School of Medicine, New York, NY 10016, 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