{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:44:11Z","timestamp":1790387051188,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["B120014"],"award-info":[{"award-number":["B120014"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"\n Tinnitus patients suffer from not only auditory sensations but also physical, mental, and social difficulties. Even though tinnitus is believed to be associated with the autonomic nervous system, changes in autonomic conditions in tinnitus patients are not receiving much research attention. The aims of this study were to investigate the autonomic condition of tinnitus patients and to consider Korean medicine in the treatment of tinnitus with an evidence-based approach. We performed a retrospective chart review and compared the heart rate variability (HRV) parameters of 40 tinnitus patients (19 acute and 21 chronic) and 40 healthy controls. In tinnitus patients, the power of the high frequency component and total power of the HRV significantly decreased\n \n \n (<\/mml:mo>\n \n P<\/mml:mi>\n <<\/mml:mo>\n 0.05<\/mml:mn>\n <\/mml:mrow>\n )<\/mml:mo>\n <\/mml:mrow>\n <\/mml:math>\n , and the low frequency to high frequency ratio significantly increased\n \n \n (<\/mml:mo>\n \n P<\/mml:mi>\n <<\/mml:mo>\n 0.05<\/mml:mn>\n <\/mml:mrow>\n )<\/mml:mo>\n <\/mml:mrow>\n <\/mml:math>\n . There was no significant difference between the acute and chronic patients. When comparing each group with the controls, there was a tendency that the longer the duration of tinnitus was, the larger the observed HRV change was. In conclusion, tinnitus patients have vagal withdrawal and sympathetic overactivity, and chronic tinnitus more strongly affects autonomic conditions than acute tinnitus. This study provides evidence for Korean medical treatments of tinnitus, such as acupuncture and Qi-training, that cause modulation of cardiac autonomic function.\n <\/jats:p>","DOI":"10.1155\/2013\/402585","type":"journal-article","created":{"date-parts":[[2013,8,19]],"date-time":"2013-08-19T17:01:16Z","timestamp":1376931676000},"page":"1-5","source":"Crossref","is-referenced-by-count":19,"title":["Autonomic Conditions in Tinnitus and Implications for Korean Medicine"],"prefix":"10.1155","volume":"2013","author":[{"given":"Eun Ji","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology of Korean Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Younghee","family":"Yun","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology of Korean Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea"},{"name":"Department of Ophthalmology, Otorhinolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungyeon","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Human Informatics of Korean Medicine, Interdisciplinary Programs, Kyung Hee University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu Seok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Otorhinolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Su","family":"Park","sequence":"additional","affiliation":[{"name":"Kyung Hee Center for Clinical Research and Drug Development, Kyung Hee University, Seoul, Republic of Korea"},{"name":"Department of Preventive Medicine, Korean Medical College, Kyung Hee University Graduate School, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inhwa","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology of Korean Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea"},{"name":"Department of Ophthalmology, Otorhinolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"11","key":"1","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.tins.2004.08.010","volume":"27","year":"2004","journal-title":"Trends in Neurosciences"},{"issue":"2","key":"2","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0030-6665(02)00160-3","volume":"36","year":"2003","journal-title":"Otolaryngologic Clinics of North America"},{"issue":"3","key":"3","doi-asserted-by":"crossref","first-page":"323","DOI":"10.35371\/kjoem.1999.11.3.323","volume":"11","year":"1999","journal-title":"Korean Journal of Occupational and Environmental Medicine"},{"key":"4","first-page":"1","volume-title":"Epidemiology of tinnitus","year":"2000"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005233.pub2"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.02.015"},{"issue":"6891","key":"7","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/bmj.306.6891.1490","volume":"306","year":"1993","journal-title":"British Medical Journal"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2009.5.1.11"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1177\/0163278710390355"},{"key":"10","year":"2004"},{"issue":"5","key":"11","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","volume":"93","year":"1996","journal-title":"Circulation"},{"issue":"1","key":"12","first-page":"20","volume":"5","year":"1999","journal-title":"International Tinnitus Journal"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2011.06.007"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.2.683"},{"issue":"383","key":"15","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1080\/01621459.1983.10478017","volume":"78","year":"1983","journal-title":"Journal of the American Statistical Association"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.02.004"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-007-0205-0"},{"issue":"3","key":"18","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s004840050036","volume":"40","year":"1997","journal-title":"International Journal of Biometeorology"},{"issue":"3","key":"19","first-page":"130","volume":"9","year":"2001","journal-title":"Central European Journal of Public Health"},{"issue":"2","key":"20","first-page":"403","volume":"16","year":"2002","journal-title":"Korean Journal of Oriental Physiology & Pathology"},{"issue":"3","key":"21","first-page":"197","volume":"25","year":"2008","journal-title":"The Journal of Korean Acupuncture & Moxibustion Society"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X02000491"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-0702(02)00150-9"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2010.12.003"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/402585.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/402585.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/402585.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,21]],"date-time":"2019-07-21T06:45:11Z","timestamp":1563691511000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ecam\/2013\/402585\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":24,"alternative-id":["402585","402585"],"URL":"https:\/\/doi.org\/10.1155\/2013\/402585","relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}