{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T17:25:40Z","timestamp":1786641940966,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,10,2]],"date-time":"2013-10-02T00:00:00Z","timestamp":1380672000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology Research International"],"published-print":{"date-parts":[[2013,10,2]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Diverticular disease of the appendix (DDA) is a rare disease and it has been shown to be associated with locoregional neoplasms. This study was conducted to characterize clinicopathological features and to investigate its association with appendiceal neoplasms. <jats:italic>Methods<\/jats:italic>. We searched the records of the Department of Pathology at Farwaniya Hospital for cases of diverticular disease of the appendix between 2003 and 2011. Histological slides and patient charts were reviewed for relevant information. Consecutive cases of acute appendicitis were selected as a control group. <jats:italic>Results<\/jats:italic>. We identified 25 cases of DDA, 24 of which occurred in men. Mean age of DDA patients was 35 \u00b1 10.1 years and was significantly greater than that of appendicitis patients (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.027<\/mml:mn><\/mml:mrow><\/mml:math>). The mean temperature of cases (37.9\u00b0) was significantly higher (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.012<\/mml:mn><\/mml:mrow><\/mml:math>) than that of the controls (37.3\u00b0). The cases had lower white blood cell (WBC) counts compared to controls (13.6 versus 16.7, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.04<\/mml:mn><\/mml:mrow><\/mml:math>). Pathological diagnosis identified 4 cases of diverticulosis, 5 cases of diverticulitis, 6 cases of diverticulosis with acute appendicitis, and 10 cases of diverticulitis and appendicitis. None of the cases was associated with any type of neoplasm. <jats:italic>Conclusions<\/jats:italic>. DDA is a rare disease, and clinicians and radiologists should be aware of it. Male sex and adult age seem to be risk factors associated with DDA. The disease may not have any direct association with any neoplasm.<\/jats:p>","DOI":"10.1155\/2013\/404308","type":"journal-article","created":{"date-parts":[[2013,10,2]],"date-time":"2013-10-02T21:07:20Z","timestamp":1380748040000},"page":"1-5","source":"Crossref","is-referenced-by-count":16,"title":["Clinicopathological Study of 25 Cases of Diverticular Disease of the Appendix: Experience from Farwaniya Hospital"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8371-812X","authenticated-orcid":true,"given":"Nabeel","family":"Al-Brahim","sequence":"first","affiliation":[{"name":"Department of Pathology, Farwaniya Hospital, P.O. Box 3313, 22034 Salmiya, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Al-Kandari","sequence":"additional","affiliation":[{"name":"Department of Surgery, Farwaniya Hospital, 81004 Sabah Al-Naser, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musaad","family":"Munahai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Farwaniya Hospital, 81004 Sabah Al-Naser, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prem","family":"Sharma","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Kuwait University, P.O. Box 24923, 13110 Safat, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"4","key":"1","first-page":"437","volume":"101","year":"1955","journal-title":"Surgery, Gynecology & Obstetrics"},{"issue":"5","key":"2","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0002-9610(05)80446-5","volume":"165","year":"1993","journal-title":"American Journal of Surgery"},{"issue":"6","key":"3","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/BF02553377","volume":"26","year":"1983","journal-title":"Diseases of the Colon and Rectum"},{"issue":"5","key":"4","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/modpathol.3880086","volume":"13","year":"2000","journal-title":"Modern Pathology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2008.06.001"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2011-200647"},{"key":"7","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archsurg.1923.01110190136008","volume":"6","year":"1923","journal-title":"Archives of Surgery"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e3180340991"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-012-0152-6"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(03)00187-9"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10023"},{"issue":"10","key":"12","first-page":"548","volume":"99","year":"1975","journal-title":"Archives of Pathology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181abe31b"}],"container-title":["Pathology Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/404308.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/404308.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/404308.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T12:49:19Z","timestamp":1607604559000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/pri\/2013\/404308\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,2]]},"references-count":13,"alternative-id":["404308","404308"],"URL":"https:\/\/doi.org\/10.1155\/2013\/404308","relation":{},"ISSN":["2090-8091","2042-003X"],"issn-type":[{"value":"2090-8091","type":"print"},{"value":"2042-003X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,2]]}}}