{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:33:53Z","timestamp":1791192833449,"version":"4.1.0"},"reference-count":139,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["167949"],"award-info":[{"award-number":["167949"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["177527"],"award-info":[{"award-number":["177527"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["129838"],"award-info":[{"award-number":["129838"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["204474"],"award-info":[{"award-number":["204474"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN210713"],"award-info":[{"award-number":["IN210713"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN201910"],"award-info":[{"award-number":["IN201910"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["167949"],"award-info":[{"award-number":["167949"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["177527"],"award-info":[{"award-number":["177527"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["129838"],"award-info":[{"award-number":["129838"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["204474"],"award-info":[{"award-number":["204474"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN210713"],"award-info":[{"award-number":["IN210713"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN201910"],"award-info":[{"award-number":["IN201910"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["167949"],"award-info":[{"award-number":["167949"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["177527"],"award-info":[{"award-number":["177527"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["129838"],"award-info":[{"award-number":["129838"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["204474"],"award-info":[{"award-number":["204474"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN210713"],"award-info":[{"award-number":["IN210713"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN201910"],"award-info":[{"award-number":["IN201910"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["167949"],"award-info":[{"award-number":["167949"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["177527"],"award-info":[{"award-number":["177527"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["129838"],"award-info":[{"award-number":["129838"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["204474"],"award-info":[{"award-number":["204474"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN210713"],"award-info":[{"award-number":["IN210713"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["IN201910"],"award-info":[{"award-number":["IN201910"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["167949"],"award-info":[{"award-number":["167949"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["177527"],"award-info":[{"award-number":["177527"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["129838"],"award-info":[{"award-number":["129838"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["204474"],"award-info":[{"award-number":["204474"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["IN210713"],"award-info":[{"award-number":["IN210713"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["IN201910"],"award-info":[{"award-number":["IN201910"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["167949"],"award-info":[{"award-number":["167949"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["177527"],"award-info":[{"award-number":["177527"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["129838"],"award-info":[{"award-number":["129838"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["204474"],"award-info":[{"award-number":["204474"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["IN210713"],"award-info":[{"award-number":["IN210713"]}]},{"name":"Programa de Apoyo a Proyectos de Investigaci\u00f3n e Innovaci\u00f3n Tecnol\u00f3gica","award":["IN201910"],"award-info":[{"award-number":["IN201910"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Curcumin is a polyphenol derived from turmeric with recognized antioxidant properties. Hexavalent chromium is an environmental toxic and carcinogen compound that induces oxidative stress. The objective of this study was to evaluate the potential protective effect of curcumin on the hepatic damage generated by potassium dichromate (K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>) in rats. Animals were pretreated daily by 9-10 days with curcumin (400\u2009mg\/kg b.w.) before the injection of a single intraperitoneal of K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>(15\u2009mg\/kg b.w.). Groups of animals were sacrificed 24 and 48\u2009h later. K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>-induced damage to the liver was evident by histological alterations and increase in the liver weight and in the activity of alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, and alkaline phosphatase in plasma. In addition, K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>induced oxidative damage in liver and isolated mitochondria, which was evident by the increase in the content of malondialdehyde and protein carbonyl and decrease in the glutathione content and in the activity of several antioxidant enzymes. Moreover, K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>induced decrease in mitochondrial oxygen consumption, in the activity of respiratory complex I, and permeability transition pore opening. All the above-mentioned alterations were prevented by curcumin pretreatment. The beneficial effects of curcumin against K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>-induced liver oxidative damage were associated with prevention of mitochondrial dysfunction.<\/jats:p>","DOI":"10.1155\/2013\/424692","type":"journal-article","created":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T21:01:06Z","timestamp":1374094866000},"page":"1-19","source":"Crossref","is-referenced-by-count":53,"title":["Curcumin Pretreatment Prevents Potassium Dichromate-Induced Hepatotoxicity, Oxidative Stress, Decreased Respiratory Complex I Activity, and Membrane Permeability Transition Pore Opening"],"prefix":"10.1155","volume":"2013","author":[{"given":"Wylly Rams\u00e9s","family":"Garc\u00eda-Ni\u00f1o","sequence":"first","affiliation":[{"name":"Department of Biology, Faculty of Chemistry, National Autonomous University of Mexico (UNAM), University City, 04510 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edilia","family":"Tapia","sequence":"additional","affiliation":[{"name":"Renal Pathophysiology Laboratory, Department of Nephrology, National Institute of Cardiology \u201cIgnacio Ch\u00e1vez\u201d, 14080 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Zazueta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Biomedicine, National Institute of Cardiology \u201cIgnacio Ch\u00e1vez\u201d, 14080 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zyanya Luc\u00eda","family":"Zatarain-Barr\u00f3n","sequence":"additional","affiliation":[{"name":"Experimental Pathology Section, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e1n\u201d, 14000 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rogelio","family":"Hern\u00e1ndez-Pando","sequence":"additional","affiliation":[{"name":"Experimental Pathology Section, National Institute of Medical Sciences and Nutrition \u201cSalvador Zubir\u00e1n\u201d, 14000 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Cecilia","family":"Vega-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Preclinical Toxicology, National Polytechnic Institute, 14740 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Pedraza-Chaverr\u00ed","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Chemistry, National Autonomous University of Mexico (UNAM), University City, 04510 Mexico City, DF, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2008.03.025"},{"issue":"1","key":"20","first-page":"44","volume":"87","year":"2004","journal-title":"Current Science"},{"key":"3","first-page":"297","volume-title":"Curcumin\u2014biological and medicinal properties","year":"2007"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2009.02086.x"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0773.2003.920106.x"},{"issue":"21","key":"118","first-page":"3832","volume":"7","year":"2008","journal-title":"African Journal of Biotechnology"},{"issue":"2","key":"62","first-page":"141","volume":"14","year":"2009","journal-title":"Alternative Medicine Review"},{"issue":"1","key":"4","first-page":"363","volume":"23","year":"2003","journal-title":"Anticancer Research"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2007.09.095"},{"issue":"2","key":"82","first-page":"G321","volume":"284","year":"2003","journal-title":"American Journal of Physiology"},{"issue":"5","key":"78","first-page":"413","volume":"64","year":"2007","journal-title":"Acta Poloniae Pharmaceutica"},{"key":"136","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2010.08.034"},{"issue":"2","key":"55","first-page":"141","volume":"20","year":"2008","journal-title":"Journal of the Egyptian National Cancer Institute"},{"issue":"9","key":"38","first-page":"4266","volume":"4","year":"2010","journal-title":"Australian Journal of Basic and Applied Sciences"},{"key":"139","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.04.016"},{"issue":"5","key":"97","first-page":"317","volume":"45","year":"2008","journal-title":"Indian Journal of Biochemistry and Biophysics"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1124\/mol.107.039818"},{"key":"115","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2008.02.005"},{"issue":"1","key":"90","doi-asserted-by":"crossref","first-page":"1","DOI":"10.17221\/2010-VETMED","volume":"52","year":"2007","journal-title":"Veterinarni Medicina"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(02)00378-5"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfm081"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s001280000224"},{"issue":"6","key":"89","first-page":"885","volume":"15","year":"2006","journal-title":"Polish Journal of Environmental Studies"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1007\/s00128-010-0124-8"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-6-4"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1186\/1476-069X-10-50"},{"issue":"11","key":"114","doi-asserted-by":"crossref","first-page":"2454","DOI":"10.1097\/00007890-200006150-00044","volume":"69","year":"2000","journal-title":"Transplantation"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2007.07.004"},{"issue":"3","key":"133","first-page":"169","volume":"102","year":"1994","journal-title":"Environmental Health Perspectives"},{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1006\/rtph.1997.1133","volume":"26","year":"1997","journal-title":"Regulatory Toxicology and Pharmacology"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1016\/S1726-4901(09)70059-0"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-8244(02)00345-0"},{"key":"84","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2009.01.003"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2010.03.013"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.3390\/cancers2020376"},{"key":"122","doi-asserted-by":"publisher","DOI":"10.1006\/taap.2000.9081"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1023\/A:1017958028256"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1002\/tox.20395"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/0742-8413(94)00103-H"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1023\/A:1017994720562"},{"issue":"1","key":"123","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1292\/jvms1939.51.137","volume":"51","year":"1989","journal-title":"Nippon Juigaku Zasshi"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2010.04.005"},{"key":"134","first-page":"65","volume":"46","year":"1991","journal-title":"Annales Universitatis Mariae Curie-Sklodowska. Sectio D"},{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-8329(00)00139-7"},{"key":"95","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/978-1-4615-0667-6_38","volume":"500","year":"2001","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(84)90718-4"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.10025"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/0165-7992(93)90106-6"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1006\/taap.1997.8151"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.07.018"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2007.04.009"},{"issue":"7","key":"65","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/BF01973713","volume":"65","year":"1991","journal-title":"Archives of Toxicology"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2010.02.012"},{"issue":"1","key":"73","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","year":"1951","journal-title":"The Journal of Biological Chemistry"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2007.12.007"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(03)00312-5"},{"key":"23","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.toxlet.2010.01.009","volume":"193","year":"2010","journal-title":"Toxicology Letters"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2003.06.002"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(00)00354-3"},{"key":"86","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.tox.2006.10.008","volume":"229","year":"2007","journal-title":"Toxicology"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(03)01948-4"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2007.09.088"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/269039"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-008-9186-2"},{"key":"141","first-page":"2938","volume":"6","year":"2012","journal-title":"Journal of Medicinal Plants Research"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2007.01.013"},{"issue":"1-2","key":"43","first-page":"119","volume":"209","year":"2000","journal-title":"Molecular and Cellular Biochemistry"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-010-9300-0"},{"key":"137","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2006.12.023"},{"key":"67","first-page":"260","volume":"2","year":"2009","journal-title":"Iranian Journal of Toxicology"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1006\/rtph.1998.1201"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/194829"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1002\/jat.1355"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(95)03199-P"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2011.08.004"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00001.2006"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2009.11.027"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2010.11.003"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2550130315"},{"issue":"5","key":"29","doi-asserted-by":"crossref","first-page":"431","DOI":"10.3109\/10408449709078442","volume":"27","year":"1997","journal-title":"Critical Reviews in Toxicology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/jat.1077"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1248\/jhs.52.142"},{"issue":"1","key":"24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0165-7992(91)90104-C","volume":"262","year":"1991","journal-title":"Mutation Research"},{"issue":"3","key":"116","first-page":"247","volume":"102","year":"1994","journal-title":"Environmental Health Perspectives"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-008-8154-3"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2005.09.008"},{"key":"6","first-page":"144","volume":"16","year":"2012","journal-title":"European Review For Medical and Pharmacological Sciences"},{"key":"120","first-page":"53","volume":"6915","year":"2013","journal-title":"Food and Chemical Toxicology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3923\/rji.2010.129.145"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-8981(03)00003-2"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2008.05.003"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200700195"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/736837"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2006000600009"},{"key":"132","first-page":"129","volume-title":"Oxidative stress in type II diabetes mellitus and the role of the endogenous antioxidant glutathione","year":"2011"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-010-0511-2"},{"key":"76","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0009-9120(99)00075-2","volume":"32","year":"1999","journal-title":"Clinical Biochemistry"},{"issue":"380-381","key":"37","first-page":"1351","year":"2006","journal-title":"Bulletin Francais de la Peche et de la Protection des Milieux Aquatiques"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2008.11.013"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2009.11.001"},{"key":"5","first-page":"17","volume":"3","year":"2011","journal-title":"American-Eurasian Journal of Toxicological Sciences"},{"key":"77","doi-asserted-by":"crossref","first-page":"S706","DOI":"10.1016\/S2221-1691(12)60300-1","volume":"2","year":"2012","journal-title":"Asian Pacific Journal of Tropical Biomedicine"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.193"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1002\/jat.763"},{"key":"124","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2003.12.013"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-008-0322-x"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2009.08.014"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00226.2004"},{"issue":"6","key":"61","first-page":"853","volume":"15","year":"2006","journal-title":"Polish Journal of Environmental Studies"},{"issue":"4","key":"59","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.aquatox.2010.08.006","volume":"100","year":"2010","journal-title":"Aquatic Toxicology"},{"key":"104","first-page":"1372","volume":"69","year":"2012","journal-title":"Acta Poloniae Pharmaceutica"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(03)00325-3"},{"issue":"12","key":"140","first-page":"1606","volume":"25","year":"2004","journal-title":"Acta Pharmacologica Sinica"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1007\/s12012-011-9128-9"},{"key":"53","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4239\/wjd.v3.i5.94","volume":"3","year":"2012","journal-title":"World Journal of Diabetes"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.2955"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.03.012"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1038\/nature05292"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2006000200004"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2007.09.002"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-007-0263-9"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.01.033"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1038\/nature09066"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2011.107"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-010-0621-4"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00467.2011"},{"issue":"3","key":"40","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1002\/hep.510310318","volume":"31","year":"2000","journal-title":"Hepatology"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1159\/000103747"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9084(02)01375-5"},{"issue":"4","key":"135","first-page":"416","volume":"35","year":"2006","journal-title":"Wei Sheng Yan Jiu"},{"issue":"11","key":"96","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1093\/carcin\/21.11.2027","volume":"21","year":"2000","journal-title":"Carcinogenesis"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-008-0335-2"},{"key":"33","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.neuint.2013.02.014","volume":"62","year":"2013","journal-title":"Neurochemistry International"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2003.12.018"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm-00000513"},{"key":"128","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/512907"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.06.006"},{"key":"126","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.09.049"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.2174\/138920112798868791"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/424692.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/424692.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2013\/424692.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T07:56:33Z","timestamp":1688370993000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ecam\/2013\/424692\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":139,"alternative-id":["424692","424692"],"URL":"https:\/\/doi.org\/10.1155\/2013\/424692","relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"value":"1741-427X","type":"print"},{"value":"1741-4288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}