{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T09:59:07Z","timestamp":1715594347080},"reference-count":30,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension.<jats:italic>Methods<\/jats:italic>. This prospective cohort study included 200 hypertensive Chinese adults aged &gt;40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mtext>IOP<\/mml:mtext><mml:mo>&gt;<\/mml:mo><mml:mn>21<\/mml:mn><\/mml:math>\u2009mmHg and\/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR).<jats:italic>Results<\/jats:italic>. The mean age of the subjects was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>64.66<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>9.47<\/mml:mn><\/mml:math>years, and the male:female ratio was 92\u2009:\u2009108. All patients were hypertensive with a mean blood pressure (BP) of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn>131.1<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>15.1<\/mml:mn><mml:mo>\/<\/mml:mo><mml:mn>76.6<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>11.1<\/mml:mn><\/mml:math>\u2009mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%.<jats:italic>Conclusion<\/jats:italic>. Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type.<\/jats:p>","DOI":"10.1155\/2013\/463710","type":"journal-article","created":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T22:01:05Z","timestamp":1358200865000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension"],"prefix":"10.1155","volume":"2013","author":[{"given":"Rita A.","family":"Gangwani","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, The University of Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Queen Mary Hospital, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacky","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, The University of Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred","family":"Kwong","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Hospital Authority, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy S. 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