{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:10Z","timestamp":1740164590151,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Critical Care"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Although uncommon during pregnancy, cirrhosis results in multiple medical complications impacting both mother and fetus. Previous reports suggest liver dysfunction in pregnancy causes accumulation of neurotoxins within the maternal compartment that increases neonatal morbidity through placental transfer. We present a case of a 36-year-old G<jats:sub>2<\/jats:sub>P<jats:sub>1<\/jats:sub>female with history of biliary cirrhosis presenting at 32-weeks' gestation with hepatic congestion progressing to hepatic encephalopathy prompting delivery. Umbilical cord sampling and postnatal infant testing demonstrated elevated ammonia levels which resolved by 12 hours of life without intervention. At discharge, the infant did not demonstrate evidence of neurologic deficit. We conclude that acute maternal hepatic encephalopathy and hyperammonemia due to chronic liver disease do not portend adverse neonatal outcomes, notably encephalopathy.<\/jats:p>","DOI":"10.1155\/2013\/507169","type":"journal-article","created":{"date-parts":[[2013,2,12]],"date-time":"2013-02-12T16:01:42Z","timestamp":1360684902000},"page":"1-3","source":"Crossref","is-referenced-by-count":0,"title":["Hyperammonemia: A Report of Maternal Biliary Cirrhosis and Neonatal Outcome"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8279-8623","authenticated-orcid":true,"given":"Deana J.","family":"Hussamy","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan A.","family":"Shivvers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Health and Hospital System, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0146-0005(98)80048-7"},{"issue":"1","key":"2","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1159\/000292444","volume":"38","year":"1994","journal-title":"Gynecologic and Obstetric Investigation"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21572"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1326.2009.01054.x"},{"volume-title":"Chronic liver disease and cirrhosis","year":"1994","key":"5"},{"year":"2009","key":"6"},{"key":"7","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1172\/JCI104891","volume":"43","year":"1964","journal-title":"The Journal of Clinical Investigation"},{"issue":"4","key":"8","first-page":"525","volume":"126","year":"1973","journal-title":"The American Journal of Diseases of Children"},{"issue":"6, supplement","key":"9","first-page":"25S","volume":"57","year":"1981","journal-title":"Obstetrics and Gynecology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2007.00144.x"}],"container-title":["Case Reports in Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2013\/507169.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2013\/507169.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cricc\/2013\/507169.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T03:24:17Z","timestamp":1498015457000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cricc\/2013\/507169\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":10,"alternative-id":["507169","507169"],"URL":"https:\/\/doi.org\/10.1155\/2013\/507169","relation":{},"ISSN":["2090-6420","2090-6439"],"issn-type":[{"type":"print","value":"2090-6420"},{"type":"electronic","value":"2090-6439"}],"subject":[],"published":{"date-parts":[[2013]]}}}