{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T12:01:01Z","timestamp":1794312061279,"version":"4.9.0"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>The aim of this study was to investigate the relationship between cardiac autonomic neuropathy (CAN) and other micro- and macrovascular complications and risk factors for type 2 diabetes. We included, in this study, 149 patients with type 2 diabetes. We evaluated their cardiovascular risk factors, demographic data, and any major micro- and macrovascular complications of their diabetes. Assessments of CAN were based upon Ewing\u2019s battery.<jats:italic>Results<\/jats:italic>. CAN was present in 38.9% of patients. In the CAN group, the duration of diabetes, BMI, systolic blood pressure, lipid levels, and HBA1c were all significantly higher than those in the other group. A significant association was found between CAN and retinopathy, peripheral neuropathy, ABI, and IMT. Multivariate logistic regression demonstrated that, in type 2 diabetes, the odds of CAN (OR (95% confidence intervals)) increase with the age of the patients (1.68 (1,4129\u20132.0025)), the average diabetes duration (0.57 (0.47\u20130.67)), cholesterol (1.009 (1.00-1.01)), HbA1c levels (1.88 (1.31\u20132.72)), peripheral neuropathy (15.47 (5.16\u201346.38)), BMI (1.12 (1.05\u20131.21)), and smoking (2.21 (1.08\u20134.53)).<jats:italic>Conclusions<\/jats:italic>. This study shows that CAN in type 2 diabetes is significantly associated with other macro- and microvascular complications and that there are important modifiable risk factors for its development.<\/jats:p>","DOI":"10.1155\/2013\/507216","type":"journal-article","created":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T16:57:31Z","timestamp":1387385851000},"page":"1-8","source":"Crossref","is-referenced-by-count":21,"title":["Cardiovascular Autonomic Neuropathy in Context of Other Complications of Type 2 Diabetes Mellitus"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4503-674X","authenticated-orcid":true,"given":"Anca","family":"Mo\u0163\u0103\u0163\u0103ianu","sequence":"first","affiliation":[{"name":"Department of Neurology, University of Medicine and Pharmacy T\u00e2rgu Mure\u015f, T\u00e2rgu Mure\u015f, Gheorghe Marinescu, No. 38, 540139, Romania"},{"name":"Mure\u015f County Clinical Emergency Hospital, T\u00e2rgu Mure\u015f, Gheorghe 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