{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:02:39Z","timestamp":1762542159334,"version":"3.37.3"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>We herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves\u2019 disease with methimazole. The patient\u2019s hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and inadequate exposure to sunlight in addition to the resolution of hyperthyroidism. Vitamin D deficiency is increasing worldwide, and it has been more recently shown to relate to the pathogenesis of Graves\u2019 disease. However, vitamin D deficiency as a cause of hypocalcemia has received little attention. Taken together, this case suggests that we should take more care in calcium kinetics and vitamin D status during treatment for Graves\u2019 disease with antithyroid drugs.<\/jats:p>","DOI":"10.1155\/2013\/512671","type":"journal-article","created":{"date-parts":[[2013,4,24]],"date-time":"2013-04-24T17:01:15Z","timestamp":1366822875000},"page":"1-4","source":"Crossref","is-referenced-by-count":6,"title":["A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves\u2019 Disease with Methimazole"],"prefix":"10.1155","volume":"2013","author":[{"given":"Kazuyuki","family":"Miyashita","sequence":"first","affiliation":[{"name":"Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, 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