{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T10:52:06Z","timestamp":1792839126861,"version":"4.5.0"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T00:00:00Z","timestamp":1370390400000},"content-version":"vor","delay-in-days":155,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"North West Wales NHS Trust"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) lead to inflammation in tendons and peritendinous tissues, but effects on biomechanical tendon function are unknown. This study investigated patellar tendon (PT) properties in stable, established RA and AS patients. <jats:italic>Methods<\/jats:italic>. We compared 18 RA patients (13 women, 59.0 \u00b1 2.8 years, mean \u00b1 SEM) with 18 age\u2010 and sex\u2010matched healthy controls (58.2 \u00b1 3.2 years), and 12 AS patients (4 women, 52.9 \u00b1 3.4 years) with 12 matched controls (54.5 \u00b1 4.7 years). Assessments with electromyography, isokinetic dynamometry, and ultrasound included quadriceps muscle force and cross\u2010sectional area (CSA), PT stiffness, and PT CSA. Additionally, measures of physical function and disease activity were performed. <jats:italic>Results<\/jats:italic>. PT stiffness and physical function were lower in RA and AS patients compared to healthy controls, without a significant difference in force production. PT CSA was significantly larger leading to reduction in Young\u2019s modulus (YM) in AS, but not in RA. <jats:italic>Conclusion<\/jats:italic>. The adverse changes in PT properties in RA and AS may contribute to their impaired physical function. AS, but not RA, leads to PT thickening without increasing PT stiffness, suggesting that PT thickening in AS is a disorganised repair process. Longitudinal studies need to investigate the time course of these changes and their response to exercise training.<\/jats:p>","DOI":"10.1155\/2013\/514743","type":"journal-article","created":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T23:21:21Z","timestamp":1370474481000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Patellar Tendon Properties and Lower Limb Function in Rheumatoid Arthritis and Ankylosing Spondylitis versus Healthy Controls: A Cross\u2010Sectional Study"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2953-8934","authenticated-orcid":false,"given":"Verena","family":"Matschke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy G.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1667-4539","authenticated-orcid":false,"given":"Andrew B.","family":"Lemmey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Maddison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6575-3711","authenticated-orcid":false,"given":"Jeanette M.","family":"Thom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,5]]},"reference":[{"key":"e_1_2_8_1_2","first-page":"28","article-title":"The \u201cside effects\u201d of rheumatoid arthritis: joint destruction, disability and early mortality","volume":"32","author":"Pincus T.","year":"1993","journal-title":"British Journal of Rheumatology"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2006.04.001"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01442.2005"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2003.00368.x"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.035576"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00059.2008"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00291.2009"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.59.12.985"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-0298-6_4"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22290"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100670200077"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(98)00038-2"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2008.03050.x"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10165-008-0129-x"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310302"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780341003"},{"key":"e_1_2_8_17_2","first-page":"1294","article-title":"Patient-centered rheumatoid arthritis disease activity assessment by a modified RADAI","volume":"35","author":"Leeb B. 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