{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T21:43:57Z","timestamp":1787607837457,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Infants born to mothers who are colonized with group B streptococcus (GBS) but received &lt;4 hours of intrapartum antibiotic prophylaxis (IAP) are at-risk for presenting later with sepsis. We assessed if &lt;4 hours of maternal IAP for GBS are associated with an increased incidence of clinical neonatal sepsis.<jats:italic>Materials and Methods<\/jats:italic>. A retrospective cohort study of women-infant dyads undergoing IAP for GBS at \u226537-week gestation who presented in labor from January 1, 2003 through December 31, 2007 was performed. Infants diagnosed with clinical sepsis by the duration of maternal IAP received (&lt; or \u22654-hours duration) were determined.<jats:italic>Results<\/jats:italic>. More infants whose mothers received &lt;4 hours of IAP were diagnosed with clinical sepsis, 13 of 1,149 (1.1%) versus 15 of 3,633 (0.4%), . Multivariate logistic regression analysis showed that treatment with \u22654 hours of IAP reduced the risk of infants being diagnosed with clinical sepsis by 65%, adjusted relative risk 0.35, CI 0.16\u20130.79, and .<jats:italic>Conclusion<\/jats:italic>. The rate of neonatal clinical sepsis is increased in newborns of GBS colonized mothers who receive &lt;4 hours compared to \u22654 hours of IAP.<\/jats:p>","DOI":"10.1155\/2013\/525878","type":"journal-article","created":{"date-parts":[[2013,3,28]],"date-time":"2013-03-28T21:03:46Z","timestamp":1364504626000},"page":"1-6","source":"Crossref","is-referenced-by-count":40,"title":["Duration of Intrapartum Antibiotics for Group B Streptococcus on the Diagnosis of Clinical Neonatal Sepsis"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3909-3131","authenticated-orcid":true,"given":"Mark A.","family":"Turrentine","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynecology, Kelsey-Seybold West Clinic, 1111 Augusta Drive, Houston, TX 77057, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Greisinger","sequence":"additional","affiliation":[{"name":"Kelsey Research Foundation, 5615 Kirby Drive, 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