{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:38:26Z","timestamp":1781671106035,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T00:00:00Z","timestamp":1387843200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology Research International"],"published-print":{"date-parts":[[2013,12,24]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. The utility of examining specimens from colorectal biopsies of polyps for nonneoplastic diseases is currently unknown. Our objectives were to characterize such additional diagnoses that could be rendered.<jats:italic>Methods<\/jats:italic>. We retrospectively and prospectively reviewed specimens from endoscopic biopsies of colorectal polyps obtained during routine screening or surveillance.<jats:italic>Results<\/jats:italic>. 17 of 168 specimens (10.1%) contained additional diagnoses, including schistosomiasis, eosinophilic colitis, intestinal spirochetosis, melanosis coli, and other entities. These findings were easily overlooked because they often affected mucosa that was spared by the polyps or were often evident only at high magnification. Schistosomiasis, eosinophilic colitis, and intestinal spirochetosis were clinically occult.<jats:italic>Conclusions<\/jats:italic>. Specimens from biopsies of colorectal polyps often harbor other diagnoses, in addition to polyps, and can be simultaneously screened for polyps and examined for nonneoplastic diseases. Detection of other diagnoses in addition to polyps requires awareness, examination at high magnification, and examination of areas spared by the polyps.<\/jats:p>","DOI":"10.1155\/2013\/570526","type":"journal-article","created":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T21:01:07Z","timestamp":1387918867000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Specimens from Biopsies of Colorectal Polyps Often Harbor Additional Diagnoses"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3611-626X","authenticated-orcid":true,"given":"Shefali","family":"Chopra","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, Irvine, CA 92868, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0565-4076","authenticated-orcid":true,"given":"Mark Li-cheng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, Irvine, CA 92868, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","year":"1992"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1309\/V2EP-TPLJ-RB3F-GHJL"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0b013e318229bfe2"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2006.02552.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1177\/1066896906296002"},{"key":"6","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1007\/s00464-012-2642-4","volume":"27","year":"2013","journal-title":"Surgical Endoscopy"},{"key":"8","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.anndiagpath.2012.10.003","volume":"17","year":"2013","journal-title":"Annals of Diagnostic Pathology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP8D7ILBHPSDOK"},{"key":"10","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/j.1365-2559.2012.04317.x","volume":"61","year":"2012","journal-title":"Histopathology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000190760.72992.ed"},{"issue":"3","key":"12","first-page":"233","volume":"20","year":"2011","journal-title":"Journal of Gastrointestinal and Liver Diseases"},{"issue":"4","key":"13","doi-asserted-by":"crossref","first-page":"544","DOI":"10.5858\/2005-129-544-SMICAL","volume":"129","year":"2005","journal-title":"Archives of Pathology and Laboratory Medicine"},{"issue":"1","key":"14","first-page":"64","volume":"104","year":"1991","journal-title":"Chinese Medical Journal"},{"issue":"5","key":"15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s15010-003-3145-y","volume":"31","year":"2003","journal-title":"Infection"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2009.10.010"},{"issue":"4","key":"17","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1136\/gut.31.4.439","volume":"31","year":"1990","journal-title":"Gut"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2011.12.004"},{"issue":"37","key":"19","doi-asserted-by":"crossref","first-page":"6077","DOI":"10.3748\/wjg.v12.i37.6077","volume":"12","year":"2006","journal-title":"World Journal of Gastroenterology"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9270(99)00837-0"},{"key":"21","first-page":"239","volume":"19","year":"2008","journal-title":"Turkish Journal of Gastroenterology"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31816ffa80"},{"key":"23","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.humpath.2012.06.011","volume":"44","year":"2013","journal-title":"Human Pathology"}],"container-title":["Pathology Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/570526.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/570526.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2013\/570526.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T15:50:39Z","timestamp":1647791439000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/pri\/2013\/570526\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,24]]},"references-count":22,"alternative-id":["570526","570526"],"URL":"https:\/\/doi.org\/10.1155\/2013\/570526","relation":{},"ISSN":["2090-8091","2042-003X"],"issn-type":[{"value":"2090-8091","type":"print"},{"value":"2042-003X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,24]]}}}