{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:12:50Z","timestamp":1790611970154,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Synovial sarcomas (SS) are aggressive malignant soft tissue tumours that are thought to arise from pluripotent mesenchymal cells.<jats:italic>Clinical Report<\/jats:italic>. A 20-year-old male presented with an acute onset of respiratory stridor. Computer tomography scanning confirmed a mass arising from the left supraglottic larynx and an emergency tracheostomy was performed. A diagnosis of biphasic synovial sarcoma was formed. A total laryngectomy and left hemithyroidectomy was performed in conjunction with a left modified radical neck dissection. The patient received adjuvant chemotherapy followed by a course of radiotherapy and remains alive and disease free at 18\u2009months after treatment.<jats:italic>Discussion<\/jats:italic>. Prognosis for patients with SS is related to primary tumour extent, grade, and size. The presence of the diagnostic translocation, t(X;18), is being targeted and hopefully will lead to the development of new therapeutics (Guadagnolo et al., 2007).<jats:italic>Conclusion<\/jats:italic>. Laryngeal SS remains a rare and poorly understood entity. A multidisciplinary approach to treatment is essential and long-term followup is imperative.<\/jats:p>","DOI":"10.1155\/2013\/578606","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T17:05:52Z","timestamp":1373303152000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["Laryngeal Synovial Sarcoma: A Rare Clinical Entity"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-5047","authenticated-orcid":true,"given":"Clair","family":"Saxby","sequence":"first","affiliation":[{"name":"St Vincents Hospital, Sydney, NSW 2010, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Bova","sequence":"additional","affiliation":[{"name":"St Vincents Clinic, Sydney, NSW 2010, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Edwards","sequence":"additional","affiliation":[{"name":"St Vincents Hospital, Sydney, NSW 2010, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00001622-200305000-00011"},{"issue":"2","key":"2","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/jso.2930540206","volume":"54","year":"1993","journal-title":"Journal of Surgical Oncology"},{"issue":"12","key":"3","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1177\/000348949810701215","volume":"107","year":"1998","journal-title":"Annals of Otology, Rhinology and Laryngology"},{"issue":"6","key":"4","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1177\/014556131008900612","volume":"89","year":"2010","journal-title":"Ear, Nose and Throat Journal"},{"key":"5","year":"2012"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.07.008"},{"key":"7","year":"2008"},{"key":"8","first-page":"52","volume":"9","year":"2011","journal-title":"Gulf Journal of Oncology"},{"key":"9","year":"2007"},{"key":"12","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1002\/(SICI)1097-0142(19990615)85:12<2596::AID-CNCR16>3.0.CO;2-K","volume":"85","year":"1999","journal-title":"Cancer"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-005-0024-z"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)08165-8"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.04.056"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20564"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-3-1"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.5694\/mja11.10947"}],"container-title":["Case Reports in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2013\/578606.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2013\/578606.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2013\/578606.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T13:07:36Z","timestamp":1563368856000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criot\/2013\/578606\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":16,"alternative-id":["578606","578606"],"URL":"https:\/\/doi.org\/10.1155\/2013\/578606","relation":{},"ISSN":["2090-6765","2090-6773"],"issn-type":[{"value":"2090-6765","type":"print"},{"value":"2090-6773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}